2-(5-Methoxy-2-methyl-1-nicotinoyl-1H-indol-3-yl)acetic acid CAS 16426-83-8
| CAS No. | 16426-83-8 |
| Molecular Formula | C18H16N2O4 |
| Molecular Weight | 324.33 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 324.33 g/mol gives 2-(5-Methoxy-2-methyl-1-nicotinoyl-1H-indol-3-yl)acetic acid distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies 2-(5-Methoxy-2-methyl-1-nicotinoyl-1H-indol-3-yl)acetic acid (CAS 16426-83-8), a certified reference material (molecular formula C18H16N2O4, MW 324.33 g/mol) for analytical method development and quality control.
The molecular framework of 2-(5-Methoxy-2-methyl-1-nicotinoyl-1H-indol-3-yl)acetic acid (C18H16N2O4) is characterized by a flavonoid core, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C18H16N2O4 |
| Molecular Weight | 324.33 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1961 |
| Nitrogen Atoms | 2 |
Related Methoxy Standards
- 3-(7-Methoxy-2-oxo-4-phenyl-2H-chromen-6-yl)propanoic acid (CAS 1043390-26-6)
- 5-Methoxy-α-oxo-6-(phenylmethoxy)-1H-indole-3-acetamide (CAS 4790-22-1)
- N-(2-methoxy-5-nitrophenyl)-2-((1-methyl-1H-tetrazol-5-yl)thio)acetamide (CAS 378225-56-0)
- 2-(((2-Methoxy-4-nitrophenyl)amino)methylene)-1H-indene-1,3(2H)-dione (CAS 351165-23-6)
- 10-Methoxy-2-methyl-3-(p-tolyl)-2,3,5,6-tetrahydro-4H-2,6-methanobenzo[g][1,3,5]oxadiazocin-4-one (CAS 892295-38-4)
- 4-Methoxy-N-(2-(5-methoxy-1H-indol-3-yl)ethyl)benzamide (CAS 363590-98-1)
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Recommended Standards
- Ethyl 4-(((1,3-dioxoisoindolin-2-yl)methyl)amino)benzoate (CAS 16320-15-3)
- 6-Hydroxy Warfarin (CAS 17834-02-5)
- Ethyl 1-(4-nitrobenzyl)-1H-indole-2-carboxylate (CAS 161466-20-2)
- 7-Hydroxy Warfarin (CAS 17834-03-6)
- 5-Chloro-2-fluoro-4-methylpyridine 5-chloro-2-fluoro-4-picoline 884494-88-6 (CAS 884494-88-6)
- N-(4-amino-2-fluorophenyl)methanesulfonamide (CAS 57164-97-3)
- 4-(sec-Butoxy)-3-methoxybenzohydrazide (CAS 1706444-90-7)
- 2-[(Benzyloxy)methyl]benzoic acid (CAS 119367-89-4)
- 1-methyl-1H,2H,3H,4H-pyrido[3,4-b]pyrazin-3-one (CAS 1384429-39-3)
- (5-Bromo-2-(trifluoromethyl)phenyl)methanol (CAS 1214349-54-8)
- N,3,5-Trimethyl-N-(4-nitrophenyl)benzamide (CAS 338757-42-9)
- 6-cyclopentyl-1,3,5-triazine-2,4-diamine (CAS 24638-58-2)
- 3-(Methylamino)pyrazine-2-carbonitrile (CAS 63352-06-7)
- Palmitoyl Tripeptide-1 HCl (CAS 2757690-14-3)
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