Lysine Impurity 22 Trihydrochloride CAS 164262-23-1
| CAS No. | 164262-23-1 |
| Molecular Formula | C12H26N4O3 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Lysine Impurity 22 Trihydrochloride.
As a process- or degradation-related impurity, Lysine Impurity 22 Trihydrochloride (CAS 164262-23-1, C12H26N4O3HCl) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Owing to an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, Lysine Impurity 22 Trihydrochloride is typically white to off-white crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 310.82 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Lysine Impurity 22 Trihydrochloride meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H26N4O3 3*HCl |
| Molecular Weight | 310.82 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 1.0 |
| CAS Registry Year (est.) | 2003 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 4 |
Related Lysine Standards
- L-Lysine Hydrochloride (CAS 10098-89-2)
- D-Lysine dihydrochloride (CAS 10303-72-7)
- Lysine Impurity 10 HCl (CAS 104584-11-4)
- L-Lysine-13C6,15N2 Hydrochloride (CAS 1200447-00-2)
- L-lysine-6-<SUP>13</SUP>C dihydrochloride (CAS 1217466-44-8)
- Lysine Impurity 25 (CAS 121893-23-0)
- Lysine Impurity 16 TFA Salt (CAS 13184-13-9(free base))
- L-Lysine-d4 Methyl Ester Dihydrochloride (CAS 1331896-92-4)
Recommended Standards
- Insulin Degludec Impurity 25 (CAS CATO-C4X-215725)
- Palbociclib Impurity 153 (CAS CATO-C4X-1125153)
- Cenobamate Impurity 45 (CAS CATO-C4X-241645)
- 1-(3,4-Dichlorophenyl)-5-imino-3-methyl-4-thioxoimidazolidin-2-one (CAS 30063-55-9)
- 2-(1-Carbamoylpiperidin-4-yl)acetic acid (CAS 279236-52-1)
- Ethyl 4,7-dibromo-8-methylquinoline-3-carboxylate (CAS 1242260-52-1)
- tert-Butyl (2-((methoxymethyl)amino)-2-oxoethyl)carbamate (CAS 496836-38-5)
- N-Methyl-N-phenylglycine (CAS 40643-55-8)
- 2-(4-Fluoro-3-iodobenzyl)guanidine (CAS 117423-43-5)
- Semaglutide impurity 74 (CAS CATO-C4X-222674)
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