[2-(4-methylphenyl)-1,3-thiazol-4-yl]acetonitrile CAS 16441-27-3

Description

As a certified reference material (CRM), [2-(4-methylphenyl)-1,3-thiazol-4-yl]acetonitrile meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

[2-(4-methylphenyl)-1,3-thiazol-4-yl]acetonitrile (CAS 16441-27-3) is a high-purity analytical reference standard with the molecular formula C12H10N2S and a molecular weight of 214.29 g/mol.

The molecular framework of [2-(4-methylphenyl)-1,3-thiazol-4-yl]acetonitrile (C12H10N2S) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

Physical & Chemical Properties

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