1-(2-Bromo-1,1-difluoroethyl)-2,4-dichlorobenzene CAS 1644456-76-7

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 1-(2-Bromo-1,1-difluoroethyl)-2,4-dichlorobenzene.

1-(2-Bromo-1,1-difluoroethyl)-2,4-dichlorobenzene (CAS 1644456-76-7) is a high-purity analytical reference standard with the molecular formula C8H5BrCl2F2 and a molecular weight of 289.93 g/mol.

The molecular framework of 1-(2-Bromo-1,1-difluoroethyl)-2,4-dichlorobenzene (C8H5BrCl2F2) is characterized by fluorine/chlorine/bromine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

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