2-Methyl-1-(3-(trifluoromethyl)phenyl)propan-2-amine hydrochloride CAS 1645-10-9
| CAS No. | 1645-10-9 |
| Molecular Formula | C11H14F3N |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 2-Methyl-1-(3-(trifluoromethyl)phenyl)propan-2-amine hydrochloride (C11H14F3NHCl) is characterized by a nitrile group, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
CATO supplies 2-Methyl-1-(3-(trifluoromethyl)phenyl)propan-2-amine hydrochloride (CAS 1645-10-9), a certified reference material (molecular formula C11H14F3NHCl, MW 253.69 g/mol) for analytical method development and quality control.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C11H14F3N HCl |
| Molecular Weight | 253.69 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
Related Methyl Standards
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- (2-Methyl-4-(trifluoromethyl)thiazol-5-yl)methanol (CAS 1000339-72-9)
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Recommended Standards
- 2-Vinyl-1H-benzo[d]imidazole (CAS 14984-26-0)
- 2-[(3,5-difluorobenzyl)thio]aniline (CAS 259132-34-8)
- N,N-Dicyclopropylmethylamine Hydrochloride (CAS 1443981-22-3)
- 4-(4-Chlorophenyl)-3-oxobutanoic acid (CAS 188817-20-1)
- 5-Bromo-4-methyl-3-((trimethylsilyl)ethynyl)pyridin-2-amine (CAS 1326216-30-1)
- 2-Chloro-8-(methylthio)-7h-purine (CAS 89581-80-6)
- 6-Fluoro-7-methyl-1H-indole-2-carbaldehyde (CAS 883531-54-2)
- 5-(Cyclopropylmethyl)-2-(methylamino)phenol (CAS 1243458-48-1)
- Ethyl 2-bromo-2-(4-methoxyphenyl)acetate (CAS 77053-56-6)
- Tirzepatide Impurity 14 (CAS CATO-C4X-324014)
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