7-Chloro-5-(2-fluorophenyl)-1,3-dihydro-2H-benzo[e][1,4]diazepine-2-thione CAS 1645-32-5
| CAS No. | 1645-32-5 |
| Molecular Formula | C15H10ClFN2S |
| Molecular Weight | 304.77 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
7-Chloro-5-(2-fluorophenyl)-1,3-dihydro-2H-benzo[e][1,4]diazepine-2-thione (CAS 1645-32-5), molecular formula C15H10ClFN2S and molecular weight 304.77 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, fluorine/chlorine substitution, 7-Chloro-5-(2-fluorophenyl)-1,3-dihydro-2H-benzo[e][1,4]diazepine-2-thione is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 304.77 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
As a certified reference material (CRM), 7-Chloro-5-(2-fluorophenyl)-1,3-dihydro-2H-benzo[e][1,4]diazepine-2-thione meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C15H10ClFN2S |
| Molecular Weight | 304.77 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
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Recommended Standards
- (4-Aminopiperidin-1-yl)(3-(3-chlorophenyl)-1H-pyrazol-5-yl)methanone (CAS 1595511-79-7)
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- ethyl 5-(chlorosulfonyl)-1-benzothiophene-2-carboxylate (CAS 1547967-32-7)
- 4-Amino-2-chloro-N-(4-propoxyphenyl)benzamide (CAS 1456386-65-4)
- 1-(4-(Dimethylamino)phenyl)-3-(1H-indol-3-yl)urea (CAS 941968-59-8)
- 1-(2-(1H-Indol-5-yl)piperidin-1-yl)ethanone (CAS 1355178-33-4)
- (3-Chloro-5-(trifluoromethyl)pyridin-2-yl)-L-alanine (CAS 1938562-70-9)
- 1,1-Diisopropoxycyclohexane (CAS 1132-95-2)
- tert-Butyl 3-acetylpiperidine-1-carboxylate (CAS 858643-92-2)
- 5-Fluoro-4-(trifluoromethyl)picolinic acid (CAS 1803834-05-0)
- 1-(Pyridin-4-ylmethyl)guanidine (CAS 45957-41-3)
- Ethyl 4-aminospiro[2.3]hexane-4-carboxylate (CAS 445306-48-9)
- 1,3-Dicyclopentylurea (CAS 58713-33-0)
- Tirzepatide Impurity 45 (CAS CATO-C4X-324045)
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