1-Methyl-3-(piperidin-4-yl)tetrahydropyrimidin-2(1H)-one CAS 164519-20-4
| CAS No. | 164519-20-4 |
| Molecular Formula | C10H19N3O |
| Molecular Weight | 197.28 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 1-Methyl-3-(piperidin-4-yl)tetrahydropyrimidin-2(1H)-one.
1-Methyl-3-(piperidin-4-yl)tetrahydropyrimidin-2(1H)-one (CAS 164519-20-4), molecular formula C10H19N3O and molecular weight 197.28 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 1-Methyl-3-(piperidin-4-yl)tetrahydropyrimidin-2(1H)-one (C10H19N3O) is characterized by an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C10H19N3O |
| Molecular Weight | 197.28 g/mol |
| Appearance | White to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 2004 |
| Nitrogen Atoms | 3 |
Related Methyl Standards
- 1-[(PIperidin-4-yl)carbonyl]piperazine (CAS 1153038-69-7)
- 1-[2-(Piperidin-1-yl)ethyl]imidazolidin-2-one (CAS 1315610-07-1)
- 1-Ethyl-3-(piperidin-3-yl)imidazolidin-2-one (CAS 1553416-12-8)
- 1-(Piperidin-4-yl)-1,4-diazepan-5-one (CAS 344779-09-5)
- 1-(Piperidin-4-yl)pyrrolidine-2-carboxamide (CAS 864356-10-5)
- 1-Methyl-4-(piperidin-4-yl)piperazin-2-one (CAS 864292-98-8)
- 4-methyl-1-(piperidin-4-yl)piperazin-2-one (CAS 870262-93-4)
- Ethyl 1-(piperidin-4-yl)cyclopropane-1-carboxylate (CAS 1024038-48-9)
Recommended Standards
- 2-Phenyl-4,5,6,7-tetrahydro-1H-indole (CAS 15582-97-5)
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- 2-methyl-1-{pyrrolo[2,1-f][1,2,4]triazin-7-yl}propan-1-one (CAS 1557912-94-3)
- n-(2-Phenylethyl)aniline (CAS 1739-00-0)
- tert-Butyl 4-(hydroxymethyl)-3-isopropyl-3,4,6,7-tetrahydro-5H-imidazo[4,5-c]pyridine-5-carboxylate (CAS 1251001-42-9)
- 3-(6-Dimethylamino-4-trifluoromethyl-pyridin-2-yl)-benzaldehyde O-methyl-oxime (CAS 1311283-85-8)
- 4-Cyano-2-fluorobenzonitrile (CAS 332099-52-2)
- 5-Bromo-3-iodo-1-(tetrahydro-2H-pyran-2-yl)-1H-indazole (CAS 1380917-35-0)
- 2-(4-Fluorophenyl)-2-phenyltetrahydrofuran (CAS 84255-03-8)
- 3-Aminomethyl-furan-2-carboxylic acid methyl ester; hydrochloride (CAS 1154012-68-6)
- 2-Hydroxyethyl cyclohexanecarboxylate (CAS 16179-44-5)
- 2-(4-Chlorophenyl)-5-iodothiazole (CAS 119514-22-6)
- N-((1-Isopropyl-1H-pyrazol-4-yl)methyl)-1,3-dimethyl-1H-pyrazol-4-amine hydrochloride (CAS 1856051-58-5)
- D-[Phe]6-Liraglutide (CAS CATO-C4X-199235)
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