1-(5-Chlorobenzofuran-2-yl)ethan-1-one CAS 1646-32-8
| CAS No. | 1646-32-8 |
| Molecular Formula | C10H7ClO2 |
| Molecular Weight | 194.61 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
1-(5-Chlorobenzofuran-2-yl)ethan-1-one (CAS 1646-32-8), molecular formula C10H7ClO2 and molecular weight 194.61 g/mol, is a CATO reference standard with documented purity and traceability.
Structurally, 1-(5-Chlorobenzofuran-2-yl)ethan-1-one (C10H7ClO2) contains a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system. The molecule exhibits a degree of unsaturation (DBE) of 7.0, corresponding to approximately 7 ring(s) or double-bond equivalent(s). With a molecular weight of 194.61 g/mol, it falls into the medium-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 1-(5-Chlorobenzofuran-2-yl)ethan-1-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H7ClO2 |
| Molecular Weight | 194.61 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | Cl-containing |
Related Chlorobenzofuran Standards
- 5-Chlorobenzofuran-2-carboxamide (CAS 35351-20-3)
- 1-(5-Chlorobenzofuran-2-yl)ethan-1-amine (CAS 147724-81-0)
- (6-Chlorobenzofuran-2-yl)boronic acid (CAS 1851286-70-8)
- (5-Chlorobenzofuran-2-yl)boronic acid (CAS 223576-64-5)
- 5-Chlorobenzofuran-2-carboxylic Acid (CAS 10242-10-1)
- 7-Chlorobenzofuran-4-carboxylic acid (CAS 1038509-42-0)
- 3-Chlorobenzofuran-5-carboxylic acid (CAS 1379278-90-6)
- 2-Chlorobenzofuran-5-carboxylic acid (CAS 860183-31-9)
Recommended Standards
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- 7-chloro-3-methyl-4H-chromen-4-one (CAS 1515294-24-2)
- (2,2-Dimethyl-1,3-dioxolan-4-yl)methyl carbonochloridate (CAS 28863-62-9)
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- 3-[(2-fluoroethanesulfonyl)methyl]azetidine hydrochloride (CAS 2044901-58-6)
- MEGA-10 (CAS 85261-20-7)
- 1-fluoro-5-methoxy-2-methyl-4-nitro-benzene (CAS 314298-13-0)
- 2-Chloroacridin-9(10H)-one (CAS 7497-52-1)
- (4-bromo-5-iodo-2-naphthyl) 2,2-dimethylpropanoate (CAS 2757096-97-0)
- 1-(Cyclopropylmethyl)-4-iodo-3-nitro-1H-pyrazole (CAS 1354704-97-4)
- 3-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)-4-methylquinoline (CAS 882747-53-7)
- tert-Butyl (2-(aminomethyl)pyridin-3-yl)carbamate (CAS 1060803-71-5)
- (Cys2)-Neuropeptide Y-8-aminooctanoyl-(D-Cys27)-Neuropeptide Y (25-32) (H-3298.0500) (CAS 128806-04-2)
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