Linagliptin Impurity 10 CAS 1646355-34-1
| CAS No. | 1646355-34-1 |
| Molecular Formula | C22H23N7O2 |
| Molecular Weight | 417.46 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Linagliptin Impurity 10 (C22H23N7O2) contains a steroid core, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
As a process- or degradation-related impurity, Linagliptin Impurity 10 (CAS 1646355-34-1, C22H23N7O2) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Linagliptin Impurity 10 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C22H23N7O2 |
| Molecular Weight | 417.46 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1993 |
| Nitrogen Atoms | 7 |
Related Linagliptin Standards
- Linagliptin Impurity 14 (CAS 666816-91-7)
- Linagliptin impurity N1 (CAS 1803079-48-2)
- Linagliptin Impurity 5 (CAS CATO-C4X-11015)
- Linagliptin Impurity 89 (CAS CATO-C4X-110189)
- Linagliptin impurity 98 (CAS CATO-C4X-110198)
- Linagliptin Impurity 30 (CAS CATO-C4X-110130)
- Linagliptin Impurity 47 (CAS 2468656-63-3)
- Linagliptin Impurity 41 (CAS 2074688-84-7)
Recommended Standards
- Thymopoietin II (32-34) (CAS 85465-82-3)
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- Levosimendan Impurity 10 (CAS CATO-C4X-130810)
- Firocoxib Impurity 15 (CAS CATO-C4X-32115)
- Indacaterol impurity 77 (CAS CATO-C4X-150077)
- Edoxaban Impurity 81 (CAS CATO-C4X-106381)
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- Methyl (4S)-2-Oxo-3-piperidin-4-yl-1,3-oxazolidine-4-carboxylate hydrochloride (CAS 1217447-70-5)
- D-Lys20-Tirzepatide (CAS CATO-CPTD788914)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com