6-Bromo-8-methoxy-3-phenyl-[1,2,4]triazolo[4,3-a]pyrazine CAS 1646649-34-4
| CAS No. | 1646649-34-4 |
| Molecular Formula | C12H9BrN4O |
| Molecular Weight | 305.13 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), 6-Bromo-8-methoxy-3-phenyl-[1,2,4]triazolo[4,3-a]pyrazine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
6-Bromo-8-methoxy-3-phenyl-[1,2,4]triazolo[4,3-a]pyrazine (CAS 1646649-34-4) is a high-purity analytical reference standard with the molecular formula C12H9BrN4O and a molecular weight of 305.13 g/mol.
The molecular framework of 6-Bromo-8-methoxy-3-phenyl-[1,2,4]triazolo[4,3-a]pyrazine (C12H9BrN4O) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, bromine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C12H9BrN4O |
| Molecular Weight | 305.13 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1993 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 4 |
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Recommended Standards
- 1-(3-Bromophenyl)-4-hydrazinyl-1H-pyrazolo[3,4-d]pyrimidine (CAS 1416348-32-7)
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- 1-(4-Bromophenyl)-4-hydrazinyl-1H-pyrazolo[3,4-d]pyrimidine (CAS 1416346-40-1)
- 2-(Cyano(2,4-dichlorophenyl)methyl)-6-fluorobenzonitrile (CAS 338965-45-0)
- (4,6-Dimethylpyrimidin-5-yl)(4-((S)-4-((1R,2R)-2-ethoxy-5-(trifluoromethyl)-2,3-dihydro-1H-inden-1-yl)-3-methylpiperazin-1-yl)-4-methylpiperidin-1-yl)methanone (CAS 869769-98-2)
- methyl 2-methyl-2H-indazole-5-carboxylate (CAS 1092351-86-4)
- 2,4-Difluoro-4-piperidinomethyl benzophenone (CAS 898775-63-8)
- 4-Amino-4-methyl-2-pentanone Oxalate (CAS 625-03-6)
- 5-[(E)-2-[(4-Chlorophenyl)amino]ethenyl]-3-(methylsulfanyl)-1,2-thiazole-4-carbonitrile (CAS 1164560-32-0)
- Phosphoric acid, monobutyl ester, potassium salt (CAS 26290-70-0)
- 2-(2-(4-Phenylpiperazin-1-yl)ethyl)isoindoline-1,3-dione (CAS 75000-24-7)
- 2-Chloro-N-(2-ethyl-6-methylphenyl)-N-(furan-2-ylmethyl)acetamide (CAS 73901-57-2)
- 2-[(2-Chlorophenyl)sulfanyl]-N-[3-fluoro-4-(morpholin-4-yl)phenyl]acetamide (CAS 866136-86-9)
- semaglutide (CAS 782487-28-9)
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