(2R,4S)-1-Tert-butyl 2-methyl 4-fluoropyrrolidine-1,2-dicarboxylate CAS 1648910-85-3
| CAS No. | 1648910-85-3 |
| Molecular Formula | C11H18FNO4 |
| Molecular Weight | 247.26 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
CATO supplies (2R,4S)-1-Tert-butyl 2-methyl 4-fluoropyrrolidine-1,2-dicarboxylate (CAS 1648910-85-3), a certified reference material (molecular formula C11H18FNO4, MW 247.26 g/mol) for analytical method development and quality control.
The molecular framework of (2R,4S)-1-Tert-butyl 2-methyl 4-fluoropyrrolidine-1,2-dicarboxylate (C11H18FNO4) is characterized by an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C11H18FNO4 |
| Molecular Weight | 247.26 g/mol |
| Appearance | White to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1993 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Recommended Standards
- (2S,4S)-1-(tert-butoxycarbonyl)-4-fluoro-2-methylpyrrolidine-2-carboxylic acid (CAS 1645565-08-7)
- 1-Isobutyl-3-(trifluoromethyl)-4,5,6,7-tetrahydro-1H-pyrazolo[4,3-c]pyridine (CAS 1706458-35-6)
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- 1-((4-(Trifluoromethyl)benzyl)oxy)butan-2-amine (CAS 1779134-91-6)
- 5-ethyl-3-{octahydropyrrolo[3,4-c]pyrrol-2-ylmethyl}-1,2,4-oxadiazole dihydrochloride (CAS 1311318-14-5)
- 1-(4,6-Difluoroindolin-1-yl)ethanone (CAS 1823489-57-1)
- Tert-butyl3-hydroxy-3-[3-(trifluoromethyl)phenyl]azetidine-1-carboxylate (CAS 1609671-73-9)
- 4-[(2-Ethoxy-2-oxoethyl)amino]-4-oxobutanoic acid (CAS 69622-18-0)
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- (2S,3S)-3-Hydroxypyrrolidine-2-carboxylic acid (CAS 4298-08-2)
- Fragment-[3-31]-Semaglutide (CAS CATO-C4X-2226113)
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