3-[(1E)-(Dimethylamino)methylidene]-1-(4-fluorophenyl)thiourea CAS 1661847-01-3
| CAS No. | 1661847-01-3 |
| Molecular Formula | C10H12FN3S |
| Molecular Weight | 225.29 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
3-[(1E)-(Dimethylamino)methylidene]-1-(4-fluorophenyl)thiourea (CAS 1661847-01-3) is a high-purity analytical reference standard with the molecular formula C10H12FN3S and a molecular weight of 225.29 g/mol.
The molecular framework of 3-[(1E)-(Dimethylamino)methylidene]-1-(4-fluorophenyl)thiourea (C10H12FN3S) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C10H12FN3S |
| Molecular Weight | 225.29 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1993 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related E Standards
- 2-(Dimethylamino)-9H-fluoren-9-ol (CAS 101089-51-4)
- 3-(Dimethylamino)-1-(naphthalen-2-yl)prop-2-en-1-one (CAS 138716-23-1)
- (2E)-3-(Dimethylamino)-1-(1-naphthyl)prop-2-en-1-one (CAS 145799-89-9)
- 4-[4-(dimethylamino)phenyl]benzaldehyde (CAS 173991-06-5)
- 1-(6-(Dimethylamino)naphthalen-2-yl)prop-2-en-1-one (CAS 86636-92-2)
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- 3-[(1E)-(Dimethylamino)methylidene]-1-(2-fluorophenyl)thiourea (CAS 477851-99-3)
- 4'-(Dimethylamino)[1,1'-biphenyl]-3-carbaldehyde (CAS 893734-60-6)
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- 2-(2-Isopropoxyphenyl)-3-methylbutan-2-ol (CAS 1443327-09-0)
- 4-Isopropoxy-3-(methoxymethyl)benzaldehyde (CAS 947012-59-1)
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