2-(4-Bromo-1H-pyrazol-3-yl)pyridine CAS 166196-52-7
| CAS No. | 166196-52-7 |
| Molecular Formula | C8H6BrN3 |
| Molecular Weight | 224.06 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
2-(4-Bromo-1H-pyrazol-3-yl)pyridine (CAS 166196-52-7) is a high-purity analytical reference standard with the molecular formula C8H6BrN3 and a molecular weight of 224.06 g/mol.
The molecular framework of 2-(4-Bromo-1H-pyrazol-3-yl)pyridine (C8H6BrN3) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, bromine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a certified reference material (CRM), 2-(4-Bromo-1H-pyrazol-3-yl)pyridine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H6BrN3 |
| Molecular Weight | 224.06 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2004 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 3 |
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Recommended Standards
- 3-Iodo-4-methylthiophene (CAS 16494-41-0)
- 4-(4-Bromo-1H-pyrazol-3-yl)pyridine (CAS 166196-54-9)
- 2-Iodo-3-methylthiophene (CAS 16494-40-9)
- (3-Styrylphenyl)boronic acid (CAS 168097-36-7)
- 1119391-69-3 5-oxo-3-(propan-2-yl)-2,5-dihydro-1H-pyrazole-1-carbothioamide MS-8755 (CAS 1119391-69-3)
- 5-Bromo-4-(piperidin-1-yl)-7H-pyrrolo[2,3-d]pyrimidine (CAS 1260838-15-0)
- N-(sec-butyl)-2-methoxypyridin-3-amine (CAS 1157649-70-1)
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