4-Fluoro-2,6-dimethylbenzoic Acid CAS 16633-50-4
| CAS No. | 16633-50-4 |
| Molecular Formula | C9H9FO2 |
| Molecular Weight | 168.16 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies 4-Fluoro-2,6-dimethylbenzoic Acid (CAS 16633-50-4), a certified reference material (molecular formula C9H9FO2, MW 168.16 g/mol) for analytical method development and quality control.
The molecular framework of 4-Fluoro-2,6-dimethylbenzoic Acid (C9H9FO2) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C9H9FO2 |
| Molecular Weight | 168.16 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1961 |
| Halogen Content | F-containing |
Related Fluoro Standards
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Recommended Standards
- 3-(2-Fluorophenyl)propionic acid (CAS 1643-26-1)
- 3-(Trifluoromethyl)piperidin-3-amine (CAS 1713668-09-7)
- (R)-2-(2-Fluorophenyl)propanoic acid (CAS 1630423-26-5)
- 2-Fluoro-2-phenylpropionic Acid (CAS 17172-46-2)
- Trimethyl(3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)prop-1-yn-1-yl)silane (CAS 129217-85-2)
- 3-[2-(Benzyloxy)ethyl]piperidine (CAS 946727-32-8)
- CAS 2260670-67-3 (CAS 2260670-67-3)
- N1-cyclopropyl-N1-((2,3-dihydrobenzo[b][1,4]dioxin-6-yl)methyl)ethane-1,2-diamine (CAS 1181739-12-7)
- 5-Methoxy-4-(2-methylphenoxy)-2-phenylpyrimidine (CAS 478029-67-3)
- methyl 3-amino-3-(2,4-difluorophenyl)propanoate hydrochloride (CAS 1333750-44-9)
- Deucravacitinib Impurity 8 (CAS CATO-C4X-31388)
- Rubusoside (CAS 64849-39-4)
- (R)-Methocarbamol (CAS 145841-69-6)
- Peptide Impurity 15 (CAS 1227750-69-7)
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