4-(2-Methylphenyl)-1,2,3,6-tetrahydropyridine CAS 166401-49-6
| CAS No. | 166401-49-6 |
| Molecular Formula | C12H15N |
| Molecular Weight | 173.25 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
4-(2-Methylphenyl)-1,2,3,6-tetrahydropyridine (CAS 166401-49-6), molecular formula C12H15N and molecular weight 173.25 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 4-(2-Methylphenyl)-1,2,3,6-tetrahydropyridine (C12H15N) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 4-(2-Methylphenyl)-1,2,3,6-tetrahydropyridine under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C12H15N |
| Molecular Weight | 173.25 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2004 |
| Nitrogen Atoms | 1 |
Related Methylphenyl Standards
- 3-methyl-2-(2-methylphenyl)butanenitrile (CAS 105902-47-4)
- 3-Methyl-2-(3-methylphenyl)butanenitrile (CAS 120352-95-6)
- 3-Methyl-2-(4-methylphenyl)butanenitrile (CAS 55291-51-5)
- 4-(3-Methylphenyl)-1,2,3,6-tetrahydropyridine (CAS 71916-52-4)
- 1-(2-methylphenyl)-1H-pyrazol-5-amine (CAS 1333801-83-4)
- 2-(4-Methylphenyl)-2H-pyrazol-3-ylamine (CAS 14678-99-0)
- 151293-15-1 5-(4-methylphenyl)-1H-pyrazol-3-amine A809157 (CAS 151293-15-1)
- 1-(2-Methylphenyl)-1H-pyrazol-4-amine (CAS 90839-85-3)
Recommended Standards
- 4-(phenylmethylidene)piperidine (CAS 164650-58-2)
- 1-Cyclopropyl-1,2,3,4-tetrahydroisoquinoline (CAS 167781-50-2)
- (1-amino-3-ethoxy-2,2-dimethylcyclobutyl)methanol (CAS 1602002-16-3)
- Methyl 2-methyl-3-[(2-methylpropyl)amino]propanoate (CAS 168209-18-5)
- (1r)-5-Chloro-2,3-dihydro-1h-inden-1-ol (CAS 1351630-00-6)
- Phenyl (4,6-Dimethoxy-2-pyrimidinyl)carbamate (CAS 89392-03-0)
- 7-Methoxy-beta-carboline-1-propionic acid (CAS 137756-13-9)
- 2,8-Bis(trifluoromethyl)-4-bromoquinoline (CAS 35853-45-3)
- 2-(4-Amino-5-(difluoromethyl)-3-iodopyridin-2-yl)acetic acid (CAS 1805149-11-4)
- (1-(Cyclohexylmethyl)piperidin-3-yl)methanol (CAS 415922-55-3)
- (2E)-4-[(3-Chlorophenyl)amino]-4-oxobut-2-enoic acid (CAS 18196-80-0)
- 4-Bromo-6-chloro-2-trifluoromethylphenol (CAS 1414870-65-7)
- 2-((2-Cyano-3-methylbutan-2-yl)amino)-2-oxoethyl 2-phenethylbenzoate (CAS 878065-68-0)
- endo-Ser39-Tirzepatide (CAS CATO-CPTD788935)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com