Bis[2-(trimethylsilyloxy)ethyl] Ether CAS 16654-74-3
| CAS No. | 16654-74-3 |
| Molecular Formula | C10H26O3Si2 |
| Molecular Weight | 250.48 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Bis[2-(trimethylsilyloxy)ethyl] Ether.
Bis[2-(trimethylsilyloxy)ethyl] Ether (CAS 16654-74-3) is a high-purity analytical reference standard with the molecular formula C10H26O3Si2 and a molecular weight of 250.48 g/mol.
The molecular framework of Bis[2-(trimethylsilyloxy)ethyl] Ether (C10H26O3Si2) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), Bis[2-(trimethylsilyloxy)ethyl] Ether meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H26O3Si2 |
| Molecular Weight | 250.48 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | -2.0 |
| CAS Registry Year (est.) | 1961 |
Related Bis Standards
- 1,2-Bis(trimethylsilyloxy)cyclohexene (CAS 6838-67-1)
- 1,2-Bis(trimethylsilyloxy)cyclobutene (CAS 17082-61-0)
- 1,1-Bis(trimethylsilyloxy)-1-propene (CAS 31469-22-4)
- 1-(Trimethylsilyloxy)-1-cyclopentyl-3-(methoxyphenyl)-methanone (CAS 1797112-95-8)
- 1-(Trimethylsilyloxy)-3,4-dihydrobenzene 2-(Trimethylsilyloxy)-1,3-cyclohexadiene 54781-19-0 T2630 (CAS 54781-19-0)
- 2-Trimethylsilyloxy-1,3-butadiene (CAS 38053-91-7)
- 3-[Tris(trimethylsilyloxy)silyl]propyl Methacrylate (CAS 17096-07-0)
Recommended Standards
- 2-Amino-4-bromo-5-chlorobenzoic acid (CAS 150812-32-1)
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- 1-Bromo-3-chloro-2-methyl-5-nitrobenzene (CAS 1448319-06-9)
- 2-Amino-3-bromo-4-chlorobenzoic acid (CAS 1698146-49-4)
- Methyl 3-(2-iodo-1H-pyrrolo[2,3-b]pyridin-3-yl)propanoate (CAS 1956382-23-2)
- 6-Bromooxazolo[5,4-b]pyridine-2(1H)-thione (CAS 120641-18-1)
- 1-(Tetrahydro-2H-pyran-4-yl)ethanamine hydrochloride (CAS 1363404-80-1)
- (4-Chloro-6-ethoxycarbonylaminopyridin-2-yl)-carbamic acid ethyl ester (CAS 63708-78-1)
- tert-Butyl 4-bromo-1H-indole-2-carboxylate (CAS 681288-90-4)
- 2-(Dimethylamino)-2-(4-isopropylphenyl)acetic acid (CAS 1103976-36-8)
- 3-(Bromomethyl)-5-(trifluoromethyl)pyridine hydrobromide (CAS 1384972-85-3)
- 2-Bromo-N-(4-(4-chlorophenyl)-1,2,5-oxadiazol-3-yl)benzamide (CAS 874146-57-3)
- N-(4-Cyano-2,3-dimethylquinolin-6-yl)acetamide (CAS 855165-86-5)
- Semaglutide Impurity 133 (CAS CATO-C4X-2226133)
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