4,4'-Bis(chloromethyl)-1,1-biphenyl CAS 1667-10-3
| CAS No. | 1667-10-3 |
| Molecular Formula | C14H12Cl2 |
| Molecular Weight | 251.15 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), 4,4'-Bis(chloromethyl)-1,1-biphenyl meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
4,4'-Bis(chloromethyl)-1,1-biphenyl (CAS 1667-10-3) is a high-purity analytical reference standard with the molecular formula C14H12Cl2 and a molecular weight of 251.15 g/mol.
Structurally, 4,4'-Bis(chloromethyl)-1,1-biphenyl (C14H12Cl2) contains chlorine substitution, a polycyclic aromatic system. The molecule exhibits a degree of unsaturation (DBE) of 8.0, corresponding to approximately 8 ring(s) or double-bond equivalent(s). With a molecular weight of 251.15 g/mol, it falls into the medium-molecular-weight range. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C14H12Cl2 |
| Molecular Weight | 251.15 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | Cl-containing |
Related Bis Standards
- 3-(chloromethyl)-1-{[2-(trimethylsilyl)ethoxy]methyl}-1H-pyrazole (CAS 913346-22-2)
- 5-(chloromethyl)-1-{[2-(trimethylsilyl)ethoxy]methyl}-1H-pyrazole (CAS 913346-47-1)
- 4-(Chloromethyl)benzyl Methanethiosulfonate (CAS 887354-05-4)
- 1-Butyl-5-(chloromethyl)-2-methanesulfonyl-1h-imidazole (CAS 1221341-13-4)
- 5-(Chloromethyl)-2-methanesulfonyl-1-(2-methylpropyl)-1h-imidazole (CAS 1221342-96-6)
- 1,3,5-Tris(chloromethyl)-2,4-dimethylbenzene (CAS 2903-00-6)
- 4-(Chloromethyl)-7-methyl-6-(1-methylethyl)-2H-1-benzopyran-2-one (CAS 568555-36-2)
- 2-(Chloromethyl)-5-(trifluoromethoxy)benzo[d]oxazole (CAS 1393644-24-0)
Recommended Standards
- 4,6-dichloro-8-oxa-3,5-diazatricyclo[7.4.0.0²,⁷]trideca-1(13),2(7),3,5,9,11-hexaene (CAS 160199-95-1)
- 5-(1,1-Difluoroethyl)-2-(trifluoromethoxy)benzonitrile (CAS 188726-03-6)
- 8-Hydroxy-5,7-dinitro-carbostyril (CAS 15450-74-5)
- 3,3'-Dichloro-2,2'-dimethyl-1,1'-biphenyl (CAS 19482-21-4)
- 4-Butyl-5-methyl-3H-pyrazol-3-one (CAS 64076-81-9)
- Boc-D-Met-OH (dicyclohexylammonium) salt (CAS 61315-59-1)
- 1-(2,3-Dihydrobenzo[b][1,4]dioxin-6-yl)cyclopropan-1-amine hydrochloride (CAS 2126176-99-4)
- 2-Bromo-6-chloroisonicotinamide (CAS 1807123-24-5)
- 2-(4-Ethyl-2,3-dioxopiperazin-1-yl)-N-(3-fluorophenyl)acetamide (CAS 868680-41-5)
- 4-((1-Methyl-1H-imidazol-5-yl)methoxy)benzaldehyde (CAS 646071-63-8)
- N-Acetylglycinamide (CAS 2620-63-5)
- 6-methoxy-7-nitro-1,2,3,4-tetrahydronaphthalen-1-one (CAS 88628-54-0)
- (R)-2-(3-bromo-5-fluorophenyl)pyrrolidine (CAS 1241683-94-2)
- Glucagon (19-29) (human, rat, porcine) (CAS 64790-15-4)
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