3-Chloro-4-ethoxy-5-fluorophenylboronic acid pinacol ester CAS 1668474-08-5
| CAS No. | 1668474-08-5 |
| Molecular Formula | C14H19BClFO3 |
| Molecular Weight | 300.56 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Based on its molecular formula C14H19BClFO3, 3-Chloro-4-ethoxy-5-fluorophenylboronic acid pinacol ester contains a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, an aromatic ring system; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 300.56 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
3-Chloro-4-ethoxy-5-fluorophenylboronic acid pinacol ester (CAS 1668474-08-5) is a high-purity analytical reference standard with the molecular formula C14H19BClFO3 and a molecular weight of 300.56 g/mol.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C14H19BClFO3 |
| Molecular Weight | 300.56 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1993 |
| Halogen Content | F/Cl-containing |
Related Chloro Standards
- 2-(4-Chloro-5-ethoxy-2-fluorophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS 1256360-15-2)
- 2-(3-Chloro-2-ethoxy-5-fluorophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS 2121511-33-7)
- 5-Chloro-4-ethoxy-2-fluorophenylboronic acid pinacol ester (CAS 2121513-68-4)
- 5-chloro-8-iodo-1,6-naphthyridine (CAS 107484-69-5)
- 4-Chloro-5-iodo-6-methyl-2-(methylthio)pyrimidine (CAS 111079-18-6)
- 1-chloro-4-iodo-2,7-naphthyridine (CAS 1234616-02-4)
- 4-chloro-2-iodo-1-methyl-1H-pyrrolo[2,3-b]pyridine (CAS 1312581-09-1)
- 4-chloro-2-iodo-7-methyl-pyrrolo[2,3-b]pyridine (CAS 1788054-66-9)
Recommended Standards
- (3-Bromo-6-chloropyridin-2-yl)methyl methanesulfonate (CAS 1823948-13-5)
- 4-Bromo-5-chloro-2-methoxybenzenesulfonamide (CAS 1208075-86-8)
- 5-bromo-3-chloro-2-methoxybenzene-1-sulfonamide (CAS 1094562-60-3)
- Dimethylbis(2,3,4,5-tetramethylcyclopenta-2,4-dien-1-yl)silane (CAS 89597-05-7)
- Methyl 3-(3-(3-amino-4-methylphenyl)-1,2,4-oxadiazol-5-yl)azetidine-1-carboxylate (CAS 1426135-82-1)
- 4-Formyl-2,6-dimethylphenyl acetate (CAS 95306-94-8)
- 4-(2-Methoxyethoxy)-3-methylbenzenesulfonamide (CAS 1094467-52-3)
- 4-Iodo-N,N-dimethyl-3-(pyridin-2-yl)-1H-pyrazole-1-sulfonamide (CAS 746668-78-0)
- BMS-856 (CAS 863382-83-6)
- 4-Dodecyl-3-methyl-1-phenyl-1H-pyrazol-5-yl ethyl carbonate (CAS 821779-83-3)
- 3-Chloro-4-(difluoromethoxy)aniline (CAS 39211-55-7)
- 4-Amino-5-chloro-6-(difluoromethyl)pyridine-2-sulfonyl chloride (CAS 1803669-24-0)
- 2,6-Difluoro-3-(Trifluoromethoxy)benzyl bromide (CAS 2244081-55-6)
- Semaglutide impurity 91 (CAS CATO-C4X-222691)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com