4-Bromo-2-thiophenecarboxylic Acid CAS 16694-18-1
| CAS No. | 16694-18-1 |
| Molecular Formula | C5H3BrO2S |
| Molecular Weight | 207.05 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 4-Bromo-2-thiophenecarboxylic Acid.
CATO supplies 4-Bromo-2-thiophenecarboxylic Acid (CAS 16694-18-1), a certified reference material (molecular formula C5H3BrO2S, MW 207.05 g/mol) for analytical method development and quality control.
The molecular framework of 4-Bromo-2-thiophenecarboxylic Acid (C5H3BrO2S) is characterized by a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, bromine substitution. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C5H3BrO2S |
| Molecular Weight | 207.05 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1961 |
| Halogen Content | Br-containing |
| Sulfur Atoms | 1 |
Related Bromo Standards
- 5-Bromo-3-thiophenecarboxylic Acid (CAS 100523-84-0)
- 5-Bromo-2-thioxo-2,3-dihydropyrimidin-4(1H)-one (CAS 113138-12-8)
- 2-Bromo-1-(1,2,4-thiadiazol-5-yl)ethanone (CAS 92845-72-2)
- 5-Bromo-2-thiophenecarboxylic Acid (CAS 7311-63-9)
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Recommended Standards
- (2,5-Dichloro-3-methoxyphenyl)methanol (CAS 165377-91-3)
- (R)-1-(3,5-Dichlorophenyl)ethane-1,2-diol (CAS 174002-82-5)
- (2,6-Dichloro-3-methoxyphenyl)methanol (CAS 160646-99-1)
- 2,6-Dichloro-1-(methoxymethoxy)benzene (CAS 1864707-50-5)
- 6-[(3,4,4-Trifluorobut-3-en-1-yl)sulfanyl]-9H-purine (CAS 478067-83-3)
- 2-Bromo-5-(3-fluorophenyl)-1,3,4-thiadiazole (CAS 412923-70-7)
- Methyl 6-bromo-4-fluoro-1h-indole-2-carboxylate (CAS 926249-89-0)
- Dapoxetine Impurity 53 (CAS 22422-27-1)
- Pemetrexed Impurity 74 (CAS CATO-C4X-172674)
- 8-(3-Azetidinyl)quinoline (CAS 1260855-14-8)
- 2-Chloro-5-(4-chlorophenyl)-1,3,4-oxadiazole (CAS 90736-28-0)
- 5-Amino-1-(4-butylphenyl)-1H-pyrazolo[3,4-d]pyrimidin-4(5H)-one (CAS 1416342-19-2)
- 1-Phenyl-3,5-bis(trifluoromethyl)-1H-pyrazole (CAS 140647-19-4)
- Ac, Gastrin Releasing Peptide (20-27), porcine (CAS 77714-20-6)
Why CATO?
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