Gadobutrol Impurity 9 CAS 16695-22-0
| CAS No. | 16695-22-0 |
| Molecular Formula | C25H29NO8S3 |
| Molecular Weight | 567.69 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Gadobutrol Impurity 9 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
As a process- or degradation-related impurity, Gadobutrol Impurity 9 (CAS 16695-22-0, C25H29NO8S3) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Structurally, Gadobutrol Impurity 9 (C25H29NO8S3) contains a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 12.0, corresponding to approximately 12 ring(s) or double-bond equivalent(s). With a molecular weight of 567.69 g/mol, it falls into the moderately-high-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Physical & Chemical Properties
| Molecular Formula | C25H29NO8S3 |
| Molecular Weight | 567.69 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1961 |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 3 |
Related Gadobutrol Standards
- Gadobutrol Impurity 8 (CAS 56187-04-3)
- Gadobutrol Impurity 5 （And Enantiomer） (CAS CATO-C4X-21205)
- Gadobutrol impurity 160 (CAS CATO-C4X-2120160)
- Gadobutrol impurity 168 (CAS CATO-C4X-2120168)
- Gadobutrol impurity 169 (CAS CATO-C4X-2120169)
- Gadobutrol Impurity 187 (CAS CATO-C4X-2120187)
- Gadobutrol Impurity 82 (CAS 137076-50-7)
- Gadobutrol Impurity 189 (CAS CATO-C4X-2120189)
Recommended Standards
- 1-Docosahexaenoyl-sn-glycero-3-phosphocholine (CAS 162440-05-3)
- 8-Ethoxy-N1,N1,N3,N3,N6,N6-hexamethylpyrene-1,3,6-trisulfonamide (CAS 127070-69-3)
- 2-Docosahexaenoyl-sn-glycero-3-phosphocholine(~90%) (CAS 159407-32-6)
- Suc-Val-Pro-Phe-SBzl (CAS 95192-51-1)
- Fluconazole EP Impurity F (CAS 118689-07-9)
- Olanzapine Impurity 47 (CAS CATO-C4X-117847)
- Phenacetin Impurity 1 (CAS 3154-18-5)
- (2,5-Dichlorophenyl)(tetrahydrofuran-3-yl)methanamine (CAS 1248787-60-1)
- 1-(4-Fluorophenyl)-3-(methylthio)propan-2-one (CAS 1183192-38-2)
- Ethyl 2-(5-(3-(4-chlorophenyl)ureido)-1,3,4-thiadiazol-2-yl)acetate (CAS 5573-64-8)
- tert-Butyl 5-methoxy-2-oxospiro[indoline-3,3'-pyrrolidine]-1'-carboxylate (CAS 862885-19-6)
- 2,3-Dibromo-1,4-diiodobenzene (CAS 1207434-10-3)
- tert-Butyl[1-(2-fluorobenzyl)piperidin-4-yl]methylcarbamate (CAS 1286264-42-3)
- 30003-72-6 insulin chain b oxidized (CAS 30003-72-6)
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