2-Phenylthiophene-3-sulphonyl chloride CAS 166964-12-1

Purity 97%+In StockPharmaceutical Standards
CAS No.166964-12-1
Molecular FormulaC10H7ClO2S2
Molecular Weight258.74 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

2-Phenylthiophene-3-sulphonyl chloride CAS 166964-12-1 chemical structure

Description

CATO supplies 2-Phenylthiophene-3-sulphonyl chloride (CAS 166964-12-1), a certified reference material (molecular formula C10H7ClO2S2, MW 258.74 g/mol) for analytical method development and quality control.

2-Phenylthiophene-3-sulphonyl chloride (C10H7ClO2S2) contains a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC10H7ClO2S2
Molecular Weight258.74 g/mol
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)7.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)2004
Halogen ContentCl-containing
Sulfur Atoms2

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