2-(Difluoromethyl)-3-fluoro-6-(methylthio)benzonitrile CAS 1672663-81-8
| CAS No. | 1672663-81-8 |
| Molecular Formula | C9H6F3NS |
| Molecular Weight | 217.21 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 2-(Difluoromethyl)-3-fluoro-6-(methylthio)benzonitrile is closely related to a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies 2-(Difluoromethyl)-3-fluoro-6-(methylthio)benzonitrile (CAS 1672663-81-8), a certified reference material (molecular formula C9H6F3NS, MW 217.21 g/mol) for analytical method development and quality control.
Structurally, 2-(Difluoromethyl)-3-fluoro-6-(methylthio)benzonitrile (C9H6F3NS) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 6.0, corresponding to approximately 6 ring(s) or double-bond equivalent(s). With a molecular weight of 217.21 g/mol, it falls into the medium-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 2-(Difluoromethyl)-3-fluoro-6-(methylthio)benzonitrile under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C9H6F3NS |
| Molecular Weight | 217.21 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1993 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Difluoromethyl Standards
- 3-(Difluoromethyl)-4-(2-methoxyethoxy)aniline (CAS 1341103-02-3)
- 2-(Difluoromethyl)-5-(2-methylthiazol-5-yl)-1,3,4-oxadiazole (CAS 2653257-14-6)
- (S)-1-(4-(difluoromethyl)-3-fluorophenyl)-2-methylpropan-1-amine (CAS 1212940-91-4)
- (S)-1-(4-(difluoromethyl)-3-fluorophenyl)butan-1-amine (CAS 1213171-89-1)
- (R)-1-(4-(difluoromethyl)-3-fluorophenyl)-2-methylpropan-1-amine (CAS 1213843-31-2)
- (R)-1-(4-(difluoromethyl)-3-fluorophenyl)butan-1-amine (CAS 1213970-14-9)
- 4-((Difluoromethyl)sulfonyl)benzonitrile (CAS 1236079-27-8)
- n-(4-((Difluoromethyl)thio)phenyl)acetamide (CAS 24933-63-9)
Recommended Standards
- 5-(Trifluoromethyl)benzo[b]thiophen-3-amine (CAS 165108-03-2)
- 4-(Trifluoromethyl)benzo[b]thiophen-3-amine (CAS 1934532-31-6)
- 6-(Trifluoromethyl)benzo[b]thiophen-3-amine (CAS 165108-01-0)
- 7-(Trifluoromethyl)benzo[b]thiophen-3-amine (CAS 1936093-67-2)
- 2-((3-Cyano-6-(4-methoxyphenyl)-4-phenylpyridin-2-yl)thio)acetic acid (CAS 94639-80-2)
- Methyl 2-hydroxy-3-(tetramethyl-1,3,2-dioxaborolan-2-yl)benzoate (CAS 1421322-59-9)
- 2-Bromo-3-chloro-5-iodobenzoic acid (CAS 875846-67-6)
- 2-Benzyl-5-nitroisoindoline (CAS 127168-68-7)
- 4-Methyl-4H-pyrrolo[3,2-b]pyridine (CAS 148807-01-6)
- (S)-Benzyl 2-((ethyl(2-hydroxyethyl)amino)methyl)pyrrolidine-1-carboxylate (CAS 1353994-10-1)
- 2,2-Dimethyl-4-oxo-4-(2,3,4,5,6-pentamethylphenyl)butanoic acid (CAS 951893-77-9)
- (3-((Pyridin-4-ylthio)methyl)phenyl)methanol (CAS 811801-40-8)
- 3-Bromo-6-methylpyridine-2-methanol (CAS 1379316-16-1)
- Semaglutide Impurity 148 (CAS CATO-C4X-2226148)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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