2H-spiro[benzofuran-3,4'-piperidine] hydrochloride CAS 167484-72-2

Purity 97%+In StockPharmaceutical Standards
CAS No.167484-72-2
Molecular FormulaC12H15NO
Molecular WeightN/A
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

2H-spiro[benzofuran-3,4'-piperidine] hydrochloride CAS 167484-72-2 chemical structure

Description

The occurrence of 2H-spiro[benzofuran-3,4'-piperidine] hydrochloride is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

2H-spiro[benzofuran-3,4'-piperidine] hydrochloride (CAS 167484-72-2) is a high-purity analytical reference standard with the molecular formula C12H15NOHCl and a molecular weight of 225.72 g/mol.

The molecular framework of 2H-spiro[benzofuran-3,4'-piperidine] hydrochloride (C12H15NOHCl) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 2H-spiro[benzofuran-3,4'-piperidine] hydrochloride meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC12H15NO HCl
Molecular Weight225.72 g/mol
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)5.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)2004
Halogen ContentCl-containing
Nitrogen Atoms1

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