6-Chloro-2-(thiophen-2-yl)quinazolin-4(1H)-one CAS 167994-99-2
| CAS No. | 167994-99-2 |
| Molecular Formula | C12H7ClN2OS |
| Molecular Weight | 262.71 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), 6-Chloro-2-(thiophen-2-yl)quinazolin-4(1H)-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
6-Chloro-2-(thiophen-2-yl)quinazolin-4(1H)-one (CAS 167994-99-2) is a high-purity analytical reference standard with the molecular formula C12H7ClN2OS and a molecular weight of 262.71 g/mol.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, chlorine substitution, 6-Chloro-2-(thiophen-2-yl)quinazolin-4(1H)-one is typically pale yellow to yellow low-melting solid. Its solid-state physicochemical attributes — including a molecular weight of 262.71 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C12H7ClN2OS |
| Molecular Weight | 262.71 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2004 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Chloro Standards
- 2-Chloro-n-[(4-sulfamoylphenyl)methyl]acetamide (CAS 101167-02-6)
- 3-Chloro-N-(4-sulfamoylphenyl)propanamide (CAS 104246-29-9)
- 2-Chloro-N,N-dimethyl-5-sulfamoylbenzamide (CAS 1099011-81-0)
- 4-Chloro-N,N-dimethyl-2-sulfamoylbenzamide (CAS 1099660-92-0)
- Methyl 2-chloro-4-methanesulfonyl-3-methylbenzoate (CAS 120100-04-1)
- N-(5-Chloro-4-cyclopropoxypyridin-3-yl)methanesulfonamide (CAS 1243349-54-3)
- N-(6-Chloro-5-cyclopropoxypyridin-2-yl)methanesulfonamide (CAS 1243377-12-9)
- N-(2-Chloro-4-cyclopropoxypyridin-3-yl)methanesulfonamide (CAS 1243396-47-5)
Recommended Standards
- Methyl 2-(2-((chlorosulfonyl)methyl)phenyl)acetate (CAS 1549872-48-1)
- Methyl 3-(allyloxy)-4-chloro-5-methoxythiophene-2-carboxylate (CAS 1708251-04-0)
- Benzyl 3-(chlorosulfonyl)propanoate (CAS 1394041-79-2)
- 3-(4-Chlorobenzenesulfonyl)butyric Acid (CAS 175205-43-3)
- 2-Methyl-4,6,8-trichloroquinoline (CAS 1204-14-4)
- 2-Methylpent-3-yn-2-amine hydrochloride (CAS 5933-08-4)
- ethyl 2,2-difluoro-2-(3-thienyl)acetate (CAS 1245643-36-0)
- H-Thr-Asp-OH (CAS 108320-97-4)
- 3-(2-Chloro-6-fluorophenyl)-6-(trifluoromethyl)-[1,2,4]triazolo[4,3-a]pyridine (CAS 311799-07-2)
- (R)-3-Amino-2-(phenylsulfonamido)propanoic acid (CAS 182301-14-0)
- [2-(4-iodophenoxy)phenyl]methanol (CAS 477886-99-0)
- 1-(1-Methyl-1h-pyrazol-4-yl)-2-(pyrrolidin-2-yl)ethan-1-ol (CAS 1427380-51-5)
- 3-Iodo-2-methyl-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrazine hydrochloride (CAS 2138044-43-4)
- Tau Peptide (379-408) trifluoroacetate salt (CAS 1246357-53-8)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com