(Z)-2-cyano-3-(1H-indol-3-yl)acrylamide CAS 168463-95-4

Purity 97%+In StockPharmaceutical Standards
CAS No.168463-95-4
Molecular FormulaC12H9N3O
Molecular Weight211.22 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

(Z)-2-cyano-3-(1H-indol-3-yl)acrylamide CAS 168463-95-4 chemical structure

Description

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

CATO supplies (Z)-2-cyano-3-(1H-indol-3-yl)acrylamide (CAS 168463-95-4), a certified reference material (molecular formula C12H9N3O, MW 211.22 g/mol) for analytical method development and quality control.

The molecular framework of (Z)-2-cyano-3-(1H-indol-3-yl)acrylamide (C12H9N3O) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

As a certified reference material (CRM), (Z)-2-cyano-3-(1H-indol-3-yl)acrylamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC12H9N3O
Molecular Weight211.22 g/mol
Purity97%+
StorageStore at 2-8°C, protect from light
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityLight-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)10.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)2005
Nitrogen Atoms3

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