2-(2,5-Dioxooxazolidin-4-yl)acetamide CAS 16875-31-3
| CAS No. | 16875-31-3 |
| Molecular Formula | C5H6N2O4 |
| Molecular Weight | 158.11 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-(2,5-Dioxooxazolidin-4-yl)acetamide.
2-(2,5-Dioxooxazolidin-4-yl)acetamide (CAS 16875-31-3) is a high-purity analytical reference standard with the molecular formula C5H6N2O4 and a molecular weight of 158.11 g/mol.
2-(2,5-Dioxooxazolidin-4-yl)acetamide (C5H6N2O4) contains a carbohydrate-derived structure, an amide group. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C5H6N2O4 |
| Molecular Weight | 158.11 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1961 |
| Nitrogen Atoms | 2 |
Related Dioxooxazolidin Standards
- (S)-3-(2,5-Dioxooxazolidin-4-yl)propanamide (CAS 33043-61-7)
- 3-(2,5-Dioxooxazolidin-4-yl)propanoic acid (CAS 3981-39-3)
- Methyl 3-(2,5-dioxooxazolidin-4-yl)propanoate (CAS 7445-27-4)
- Benzyl ((2,5-dioxooxazolidin-4-yl)methyl)carbamate (CAS 76421-05-1)
- 2-(2,5-Dioxooxazolidin-4-yl)acetic acid (CAS 6542-24-1)
Recommended Standards
- Methyl 2,5-dioxoimidazolidine-4-carboxylate (CAS 156514-01-1)
- 2,6-Difluoronicotinamide (CAS 171178-51-1)
- DL-Dihydro-Orotic Acid (CAS 155-54-4)
- 4,6-Difluoronicotinamide (CAS 1823869-07-3)
- 2-(2-Chloropyridin-4-yl)-1,1,1,3,3,3-hexafluoropropan-2-ol (CAS 1402599-02-3)
- tert-Butyl (4-aminobut-2-en-1-yl)carbamate (CAS 1807939-98-5)
- (E)-[(5-Chloro-1,3-dimethyl-1H-pyrazol-4-yl)methylidene]amino 4-fluorobenzoate (CAS 477709-09-4)
- Ceftazidime impurity 121 (CAS CATO-C4X-1212121)
- (S)-2-((2-fluorophenoxy)methyl)piperazine (CAS 2387565-47-9)
- (E)-2-(2-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)vinyl)aniline (CAS 2661398-11-2)
- N-(2,4-dimethoxybenzyl)-1-(furan-2-yl)methanamine (CAS 510723-66-7)
- 2-Cyclopropoxy-6-methoxybenzoic acid (CAS 1243469-93-3)
- (E)-2-(Trityloxyimino)-2-[2-(tritylamino)thiazol-4-yl]acetic Acid (CAS 69689-81-2)
- Neuropeptide Y (18-36) (CAS 114495-97-5)
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