8-Bromo-4-chloro-5-fluoroquinoline-2-carboxylic acid CAS 1695285-00-7
| CAS No. | 1695285-00-7 |
| Molecular Formula | C10H4BrClFNO2 |
| Molecular Weight | 304.50 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 8-Bromo-4-chloro-5-fluoroquinoline-2-carboxylic acid.
CATO supplies 8-Bromo-4-chloro-5-fluoroquinoline-2-carboxylic acid (CAS 1695285-00-7), a certified reference material (molecular formula C10H4BrClFNO2, MW 304.50 g/mol) for analytical method development and quality control.
The molecular framework of 8-Bromo-4-chloro-5-fluoroquinoline-2-carboxylic acid (C10H4BrClFNO2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine/bromine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 8-Bromo-4-chloro-5-fluoroquinoline-2-carboxylic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C10H4BrClFNO2 |
| Molecular Weight | 304.50 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1994 |
| Halogen Content | F/Cl/Br-containing |
| Nitrogen Atoms | 1 |
Related Bromo Standards
- 3-Bromo-2-chloro-8-fluoroquinoline-4-carboxylic acid (CAS 1437385-33-5)
- 3-Bromo-2-chloro-6-fluoroquinoline-4-carboxylic acid (CAS 1437433-63-0)
- 3-Bromo-1-(3-chloro-4-fluorophenyl)-1H-pyrrole-2,5-dione (CAS 1706459-74-6)
- 2-Bromo-6-chloro-3-fluoroquinoline-4-carboxylic acid (CAS 834884-14-9)
- 6-Bromo-4-chloro-7-fluoroquinoline-3-carboxylic acid (CAS 2385600-04-2)
- 5-Bromo-2-(6-chloropyridazin-3-yl)-2H-1,2,3-triazole-4-carboxylic acid (CAS 1774898-90-6)
- 6-Bromo-7-(2-chloroacetyl)-2h-benzo[b][1,4]oxazin-3(4h)-one (CAS 1094432-20-8)
- methyl 5-bromo-2-(chloromethyl)-1,3-benzoxazole-7-carboxylate (CAS 1221792-54-6)
Recommended Standards
- 1-(3,4-dihydro-2H-thiochromen-8-yloxy)-3-[[1,1,1,3,3,3-hexadeuterio-2-(trideuteriomethyl)propan-2-yl]amino]propan-2-ol (CAS 1795037-66-9)
- 4,5-Bis(2-cyanoethylthio)-1,3-dithiole-2-thione (CAS 132765-35-6)
- 1-Methyl-4-(3-(triethoxysilyl)propyl)piperazine (CAS 67154-24-9)
- 5-methoxy-1-(triisopropylsilyl)-1H-pyrrolo[2,3-b]pyridine (CAS 1198097-37-8)
- tert-butyl 1-oxo-6-azaspiro[3.4]octane-6-carboxylate (CAS 1251010-17-9)
- Methyl 4,6-dimethyl-3-nitropicolinate (CAS 342625-14-3)
- 1-Isothiocyanato-6-(methylthio)-hexane (CAS 4430-39-1)
- 2-Isobutyl-4,5,6,7-tetrahydro-2H-pyrazolo[4,3-c]pyridin-3-ol (CAS 1708401-36-8)
- Ethyl 2-cyano-3,3-diethoxyprop-2-enoate (CAS 1146943-46-5)
- N-(3,4-dimethoxyphenyl)-N-(methylsulfonyl)glycine (CAS 363174-13-4)
- 5-(3-Fluoro-4-methoxyphenyl)-6-methyl-2-(methylthio)-[1,2,4]triazolo[1,5-a]pyrimidine (CAS 861210-14-2)
- Methyl 4-methoxybenzimidate hydrochloride (CAS 39739-49-6)
- 7-Chloro-4-(3-phenylpropyl)-4,5-dihydrobenzo[f][1,4]oxazepin-3(2H)-one (CAS 1326864-70-3)
- Semaglutide Impurity 138 (CAS CATO-C4X-2226138)
Why CATO?
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