2-(5-Fluoro-1H-indol-1-yl)ethan-1-amine CAS 169673-84-1

Purity 97%+In StockPharmaceutical Standards
CAS No.169673-84-1
Molecular FormulaC10H11FN2
Molecular Weight178.21 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

2-(5-Fluoro-1H-indol-1-yl)ethan-1-amine CAS 169673-84-1 chemical structure

Description

The molecular framework of 2-(5-Fluoro-1H-indol-1-yl)ethan-1-amine (C10H11FN2) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

CATO supplies 2-(5-Fluoro-1H-indol-1-yl)ethan-1-amine (CAS 169673-84-1), a certified reference material (molecular formula C10H11FN2, MW 178.21 g/mol) for analytical method development and quality control.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC10H11FN2
Molecular Weight178.21 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor)
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)6.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)2005
Halogen ContentF-containing
Nitrogen Atoms2

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