(2R,3R,4S,5R,6R)-2-(acetoxymethyl)-6-(2-chloroethoxy)tetrahydro-2H-pyran-3,4,5-triyl triacetate CAS 16977-77-8
| CAS No. | 16977-77-8 |
| Molecular Formula | C16H23ClO10 |
| Molecular Weight | 410.80 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of (2R,3R,4S,5R,6R)-2-(acetoxymethyl)-6-(2-chloroethoxy)tetrahydro-2H-pyran-3,4,5-triyl triacetate is closely related to a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
(2R,3R,4S,5R,6R)-2-(acetoxymethyl)-6-(2-chloroethoxy)tetrahydro-2H-pyran-3,4,5-triyl triacetate (CAS 16977-77-8), molecular formula C16H23ClO10 and molecular weight 410.80 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of (2R,3R,4S,5R,6R)-2-(acetoxymethyl)-6-(2-chloroethoxy)tetrahydro-2H-pyran-3,4,5-triyl triacetate (C16H23ClO10) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C16H23ClO10 |
| Molecular Weight | 410.80 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at room temperature, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1961 |
| Halogen Content | Cl-containing |
Recommended Standards
- (2R,3S,4S,5R,6R)-2-(acetoxymethyl)-6-(2-chloroethoxy)tetrahydro-2H-pyran-3,4,5-triyl triacetate (CAS 140428-85-9)
- (2R,3R,4S,5S,6S)-2-(acetoxymethyl)-6-(2-chloroethoxy)tetrahydro-2H-pyran-3,4,5-triyl triacetate (CAS 849420-02-6)
- N-(4-Chloro-3-pyridyl)-4-[[2,2-difluorobenzo[d][1,3]dioxol-5-yl]methyl]piperazine-1-carboxamide (CAS 1346528-50-4)
- (5-((4-Chlorobenzyl)sulfonyl)-1-methyl-3-(trifluoromethyl)-1H-pyrazol-4-yl)methyl acetate (CAS 318469-50-0)
- Benzyl cyclopropyl(2-(methylamino)cyclohexyl)carbamate (CAS 1353977-47-5)
- 3-(3-cyclohexyl-1H-1,2,4-triazol-5-yl)pyridine (CAS 942025-97-0)
- 1-(4-(Trifluoromethyl)phenyl)piperazin-2-one hydrochloride (CAS 312936-87-1)
- 2-Hydroxyeupatolide (CAS 72229-33-5)
- 2-Bromododec-1-ene (CAS 74571-85-0)
- (E)-2-[(4-chlorophenyl)sulfonyl]-3-(6-nitro-1,3-benzodioxol-5-yl)-2-propenenitrile (CAS 929982-16-1)
- o-(4-(Trifluoromethoxy)benzyl)hydroxylamine (CAS 535975-99-6)
- 11H-Benz[bc]aceanthrylene (CAS 202-94-8)
- Torasemide impurity 32 (CAS CATO-C4X-183632)
- Semaglutide impurity 208 (CAS CATO-C4X-2226208)
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