1-Boc-2-(2,6-difluorobenzyl)hydrazine CAS 1699360-88-7
| CAS No. | 1699360-88-7 |
| Molecular Formula | C12H16F2N2O2 |
| Molecular Weight | 258.26 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 1-Boc-2-(2,6-difluorobenzyl)hydrazine (C12H16F2N2O2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
1-Boc-2-(2,6-difluorobenzyl)hydrazine (CAS 1699360-88-7) is a high-purity analytical reference standard with the molecular formula C12H16F2N2O2 and a molecular weight of 258.26 g/mol.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 1-Boc-2-(2,6-difluorobenzyl)hydrazine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H16F2N2O2 |
| Molecular Weight | 258.26 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1994 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Boc Standards
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- n-(2,6-Difluorobenzyl)-2-morpholinoethan-1-amine (CAS 1019569-30-2)
- 2-(4-(2,3-Difluorobenzyl)piperazin-1-yl)ethan-1-ol (CAS 1223214-21-8)
- 2-(1-(2,3-Difluorobenzyl)piperazin-2-yl)ethan-1-ol (CAS 815622-67-4)
- 2-(1-(3,4-Difluorobenzyl)piperazin-2-yl)ethan-1-ol (CAS 815603-03-3)
- 1-(2,4-Difluorobenzyl)piperidine-4-carboxylic acid (CAS 901922-89-2)
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Recommended Standards
- tert-Butyl 2-(2,4-difluorobenzyl)hydrazinecarboxylate (CAS 1692161-25-3)
- (1aα,6β,10bα)-1,1-Difluoro-1,1a,6,10b-tetrahydrodibenzo[a,e]cyclopropa[c]cyclohepten-6-ol (CAS 172925-68-7)
- Ethyl 5-(2,6-difluorophenoxy)pentanoate (CAS 1443353-72-7)
- 5-Methyl-4-(2-trifluoromethylphenyl)-thiazol-2-ylamine (CAS 1781349-81-2)
- 7,8-Dimethyl-11-(4-nitrophenyl)-2,3,4,5,10,11-hexahydro-1H-dibenzo[b,e][1,4]diazepin-1-one (CAS 338748-17-7)
- Benzylmethyl((2S)-3-methyl-1-(pyrrolidin-1-yl)pentan-2-yl)carbamate (CAS 959574-91-5)
- 2-Ethylpyrazole-3-carbaldehyde (CAS 902837-62-1)
- 3-(tert-Butoxy)-4-hydroxybenzamide (CAS 1243279-41-5)
- Benzyl 3-(mercaptomethyl)pyrrolidine-1-carboxylate, 95% (CAS 1353981-84-6)
- 6-Methyl-1-(methylsulfonyl)-1,2,3,4-tetrahydroquinolin-4-ol (CAS 88131-74-2)
- tert-Butyl ((1R,2S)-2-(hydroxymethyl)cyclopropyl)carbamate (CAS 162129-49-9)
- 2,6-Dimethyl-1-naphthaldehyde (CAS 856203-51-5)
- 4-Iododiphenylmethane (CAS 35444-94-1)
- Amyloid Precursor Frameshift Mutant C-Terminal Peptide trifluoroacetate salt (CAS 189125-14-2)
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