(3R,4S)-tert-Butyl 3-amino-4-fluoropiperidine-1-carboxylate CAS 1700611-18-2

Description

Compared with other compounds in its class, the molecular weight of 218.27 g/mol gives (3R,4S)-tert-Butyl 3-amino-4-fluoropiperidine-1-carboxylate distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

(3R,4S)-tert-Butyl 3-amino-4-fluoropiperidine-1-carboxylate (CAS 1700611-18-2) is a high-purity analytical reference standard with the molecular formula C10H19FN2O2 and a molecular weight of 218.27 g/mol.

The molecular framework of (3R,4S)-tert-Butyl 3-amino-4-fluoropiperidine-1-carboxylate (C10H19FN2O2) is characterized by an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

CATO manufactures (3R,4S)-tert-Butyl 3-amino-4-fluoropiperidine-1-carboxylate under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

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