5-(tetramethyl-1,3,2-dioxaborolan-2-yl)-2-(trifluoromethyl)pyrimidine CAS 1701434-52-7
| CAS No. | 1701434-52-7 |
| Molecular Formula | C11H20BF3N2O2 |
| Molecular Weight | 280.09 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Structurally, 5-(tetramethyl-1,3,2-dioxaborolan-2-yl)-2-(trifluoromethyl)pyrimidine (C11H20BF3N2O2) contains an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 1.5, corresponding to approximately 1 ring(s) or double-bond equivalent(s). With a molecular weight of 280.09 g/mol, it falls into the medium-molecular-weight range. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
5-(tetramethyl-1,3,2-dioxaborolan-2-yl)-2-(trifluoromethyl)pyrimidine (CAS 1701434-52-7) is a high-purity analytical reference standard with the molecular formula C11H20BF3N2O2 and a molecular weight of 280.09 g/mol.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C11H20BF3N2O2 |
| Molecular Weight | 280.09 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 1.5 |
| CAS Registry Year (est.) | 1994 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related tetramethyl Standards
- 4-(tetramethyl-1,3,2-dioxaborolan-2-yl)-1-(2,2,2-trifluoroethyl)-1H-pyrazole (CAS 1049730-42-8)
- 1-methyl-4-(tetramethyl-1,3,2-dioxaborolan-2-yl)-5-(trifluoromethyl)-1H-pyrazole (CAS 1353003-51-6)
- Methyl 3-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl)propanoate (CAS 1093307-33-5)
- 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)quinoline-7-carbonitrile (CAS 1231926-31-0)
- 8-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)isoquinoline-3-carbonitrile (CAS 2378308-06-4)
- 7-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-3H-quinazolin-4-one (CAS 1009303-80-3)
- Methyl 2-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)cyclohex-3-en-1-yl]acetate (CAS 1109277-66-8)
- (E)-4,4,5,5-Tetramethyl-2-(2-(naphthalen-2-yl)vinyl)-1,3,2-dioxaborolane (CAS 1259026-15-7)
Recommended Standards
- 2-Hydrazinyl-5-nitro-3-(tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine (CAS 1416061-91-0)
- {4-[5-(4-Methylphenyl)-1,2,4-oxadiazol-3-yl]phenyl}boronic acid (CAS 2377609-92-0)
- 2-Hydrazinyl-3-nitro-5-(tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine (CAS 1356829-95-2)
- 2-(5-Benzyl-1,2,4-oxadiazol-3-yl)phenylboronic acid (CAS 2377609-83-9)
- 3-Methoxy-1-(1-(5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyridin-3-yl)ethyl)-1H-pyrazol-4-amine (CAS 1443278-70-3)
- Ethyl 2-amino-3,3,3-trifluoro-2-methylpropanoate (CAS 1513588-93-6)
- N-(3,5-dimethylphenyl)-8-methyl-4H-thieno[3,2-c]thiochromene-2-carboxamide (CAS 477887-17-5)
- (3aS,7aS)-Octahydro-1H-indole (CAS 753416-80-7)
- (3R,4R)-1-(tert-Butoxycarbonyl)-4-(4-fluorophenyl)pyrrolidine-3-carboxylic acid (CAS 455954-94-6)
- XPhos Palladacycle Gen. 1 (CAS 1334385-47-5)
- 3-(1-Methylhydrazinyl)pyridine (CAS 99979-60-9)
- Ethyl 7-(difluoromethyl)-5-(2-methoxyphenyl)pyrazolo[1,5-a]pyrimidine-3-carboxylate (CAS 754230-33-6)
- 1-(oxan-4-yl)azetidine-3-carboxylic acid (CAS 1127402-33-8)
- GnRH Associated Peptide (GAP) (1-13), human (CAS 100111-07-7)
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