5-Chloro-1-(4-fluorophenyl)-1H-indol-3-yl acetate CAS 170232-37-8
| CAS No. | 170232-37-8 |
| Molecular Formula | C16H11ClFNO2 |
| Molecular Weight | 303.72 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO supplies 5-Chloro-1-(4-fluorophenyl)-1H-indol-3-yl acetate (CAS 170232-37-8), a certified reference material (molecular formula C16H11ClFNO2, MW 303.72 g/mol) for analytical method development and quality control.
Structurally, 5-Chloro-1-(4-fluorophenyl)-1H-indol-3-yl acetate (C16H11ClFNO2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 11.0, corresponding to approximately 11 ring(s) or double-bond equivalent(s). With a molecular weight of 303.72 g/mol, it falls into the moderately-high-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C16H11ClFNO2 |
| Molecular Weight | 303.72 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2005 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
Related Chloro Standards
- 1-(2-Chloro-6-fluorobenzyl)-1H-indole-3-carboxylic acid (CAS 1226365-40-7)
- (1-(3-Chloro-4-fluorophenyl)-3-(pyridin-3-yl)-1H-pyrazol-4-yl)methanol (CAS 618444-58-9)
- 1-(4-Chloro-3-nitrobenzenesulfonyl)-2-methyl-4,5-dihydro-1H-imidazole (CAS 312279-47-3)
- 2-(3-Chloro-1-benzothiophen-2-yl)-6h,7h-[1,3]oxazolo[5,4-d]pyrimidin-7-one (CAS 937600-48-1)
- 2-Chloro-6-(benzylsulfanyl)-4-(trifluoromethyl)pyridine (CAS 1303889-57-7)
- 4-Chloro-2-((2-(trifluoromethyl)benzyl)thio)pyridine (CAS 1346707-59-2)
- 4-Chloro-2-((3-(trifluoromethyl)benzyl)thio)pyridine (CAS 1346707-61-6)
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Recommended Standards
- 2,4-Dioxo-1-propyl-1,2,3,4-tetrahydropyrido[2,3-d]pyrimidine-6-sulfonyl chloride (CAS 1334149-09-5)
- 4-Chloro-N-(2,5-difluorophenyl)benzenesulfonamide (CAS 290331-05-4)
- 1-[4-(Chlorosulfonyl)phenyl]-5-oxopyrrolidine-3-carboxylic acid (CAS 874496-79-4)
- 3-Chloro-N-(2,5-dimethyl-1H-pyrrol-1-yl)-N-methyl-5-(trifluoromethyl)pyridin-2-amine (CAS 860784-06-1)
- 2,6-Dichloro-4-methoxyquinoline (CAS 952434-99-0)
- 3-(2,3,4-Trifluorophenyl)pyridin-4-amine (CAS 1258624-27-9)
- 4-Allyl-5-(biphenyl-2-yloxymethyl)-4H-[1,2,4]triazole-3-thiol (CAS 722464-03-1)
- 1-Bromo-2-methyl-5-nitro-3-(trifluoromethyl)benzene (CAS 1219948-34-1)
- Azulen-2-amine (CAS 50472-20-3)
- Budesonide Impurity 27 (CAS 2396-43-2)
- 2,6-Dibromo-4-hydroxybenzoic acid (CAS 1935194-66-3)
- [2-(4-fluorophenyl)-5-methyl-1,3-oxazol-4-yl]methanamine (CAS 1048917-47-0)
- 3-(1,3-Benzothiazol-2-yl-2,3-Difluoroacrylonitrile (CAS 26418-15-5)
- Semaglutide impurity 290 (CAS CATO-C4X-2226290)
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