7-Chloro-3-iodo-1H-indole CAS 1702876-77-4
| CAS No. | 1702876-77-4 |
| Molecular Formula | C8H5ClIN |
| Molecular Weight | 277.49 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 277.49 g/mol gives 7-Chloro-3-iodo-1H-indole distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
7-Chloro-3-iodo-1H-indole (CAS 1702876-77-4) is a high-purity analytical reference standard with the molecular formula C8H5ClIN and a molecular weight of 277.49 g/mol.
The molecular framework of 7-Chloro-3-iodo-1H-indole (C8H5ClIN) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine/iodine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 7-Chloro-3-iodo-1H-indole under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C8H5ClIN |
| Molecular Weight | 277.49 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1994 |
| Halogen Content | Cl/I-containing |
| Nitrogen Atoms | 1 |
Related Chloro Standards
- 4-Chloro-7-iodo-1H-indole (CAS 1000341-82-1)
- 2-(4-Chloro-3-iodophenyl)acetonitrile (CAS 104317-97-7)
- 7-Chloro-4-iodo-1H-indole (CAS 1167055-57-3)
- 6-Chloro-5-iodo-1H-indole (CAS 122509-74-4)
- 5-Chloro-7-iodo-1H-indole (CAS 1262770-19-3)
- 5-Chloro-2-iodoindole (CAS 1388032-50-5)
- 5-Chloro-2-iodo-2H-indole (CAS 1388032-50-6)
- 5-Chloro-2-iodo-3H-indole (CAS 1388032-50-7)
Recommended Standards
- 2,4,8-Trichloro-3-nitroquinoline (CAS 1447953-51-6)
- 2-(2,2-Dicyclohexylethyl)piperidine (CAS 39648-48-1)
- 3-Chloro-4-iodo-1H-indole (CAS 1447607-33-1)
- 2,4,6-Trichloro-3-nitroquinoline (CAS 259180-81-9)
- N-(2-Hydrazinyl-2-oxoethyl)benzo[c][1,2,5]thiadiazole-4-sulfonamide (CAS 175203-26-6)
- 2-(3-(((Cyclopropylmethyl)amino)methyl)piperidin-1-yl)ethanol (CAS 1353970-93-0)
- 4-(Pyrrolidin-1-yl)butan-2-one (CAS 33598-33-3)
- 3,7-Di-tert-butyl-10H-phenothiazine (CAS 27075-55-4)
- 3-Propoxy-1-(3-(trifluoromethyl)phenyl)-1H-pyrazolo[3,4-b]pyridine (CAS 34614-30-7)
- Potassium 3,4-dibromo-2-thienyltrifluoroborate (CAS 1401522-75-5)
- 1-(4-Chlorophenyl)pyrrolidin-2-one (CAS 7661-33-8)
- [2-chloro-6-(1H-imidazol-1-yl)phenyl]methanamine dihydrochloride (CAS 1909319-89-6)
- Plerixafor Impurity 16 (CAS CATO-C4X-113316)
- Semaglutide impurity 247 (CAS CATO-C4X-2226247)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com