(4-((1,4-Dioxa-8-azaspiro[4.5]Decan-8-yl)methyl)-3-fluorophenyl)boronic acid CAS 1704074-38-3
| CAS No. | 1704074-38-3 |
| Molecular Formula | C14H19BFNO4 |
| Molecular Weight | 295.11 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO supplies (4-((1,4-Dioxa-8-azaspiro[4.5]Decan-8-yl)methyl)-3-fluorophenyl)boronic acid (CAS 1704074-38-3), a certified reference material (molecular formula C14H19BFNO4, MW 295.11 g/mol) for analytical method development and quality control.
The molecular framework of (4-((1,4-Dioxa-8-azaspiro[4.5]Decan-8-yl)methyl)-3-fluorophenyl)boronic acid (C14H19BFNO4) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C14H19BFNO4 |
| Molecular Weight | 295.11 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1994 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Dioxa Standards
- (3-((1,4-Dioxa-8-azaspiro[4.5]Decan-8-yl)methyl)-5-fluorophenyl)boronic acid (CAS 1704074-61-2)
- (4-((1,4-Dioxa-8-azaspiro[4.5]Decan-8-yl)methyl)-2-fluorophenyl)boronic acid (CAS 1704121-92-5)
- 1-(1,5-Dioxa-9-azaspiro[5.5]undecan-9-yl)-3-(thiophen-3-yl)prop-2-en-1-one (CAS 1351664-87-3)
- Ethyl 4-(1,4-dioxa-8-azaspiro[4.5]Decan-8-yl)benzoate (CAS 79421-38-8)
- 2,2'-(1,7-Dioxa-4,10-diazacyclododecane-4,10-diyl)diacetic acid (CAS 86952-03-6)
- 2-Phenyl-9,12-dioxa-1,2,4-triazadispiro[4.2.4(8).2(5)]Tetradecan-3-one (CAS 338773-04-9)
- 9-Acetyl-1,4-dioxa-12-thia-9-azadispiro[4.2.4(8).2(5)]Tetradecane-10-carboxylic acid (CAS 1025707-45-2)
- (2-((1,4-Dioxa-8-azaspiro[4.5]Decan-8-yl)methyl)phenyl)(cyclopropyl)methanone (CAS 898781-11-8)
Recommended Standards
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