(3-Chloro-4-(piperazin-1-ylmethyl)phenyl)boronic acid hydrochloride CAS 1704074-52-1
| CAS No. | 1704074-52-1 |
| Molecular Formula | C11H16BClN2O2 |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including (3-Chloro-4-(piperazin-1-ylmethyl)phenyl)boronic acid hydrochloride.
(3-Chloro-4-(piperazin-1-ylmethyl)phenyl)boronic acid hydrochloride (CAS 1704074-52-1) is a high-purity analytical reference standard with the molecular formula C11H16BClN2O2HCl and a molecular weight of 290.98 g/mol.
The molecular framework of (3-Chloro-4-(piperazin-1-ylmethyl)phenyl)boronic acid hydrochloride (C11H16BClN2O2HCl) is characterized by an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), (3-Chloro-4-(piperazin-1-ylmethyl)phenyl)boronic acid hydrochloride meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C11H16BClN2O2 HCl |
| Molecular Weight | 290.98 g/mol |
| Appearance | White to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 3.5 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1994 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
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