4-(3-Bromo-5-fluorophenyl)piperazin-1-ol CAS 1704080-86-3
| CAS No. | 1704080-86-3 |
| Molecular Formula | C10H12BrFN2O |
| Molecular Weight | 275.12 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
4-(3-Bromo-5-fluorophenyl)piperazin-1-ol (CAS 1704080-86-3), molecular formula C10H12BrFN2O and molecular weight 275.12 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 4-(3-Bromo-5-fluorophenyl)piperazin-1-ol (C10H12BrFN2O) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/bromine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
As a certified reference material (CRM), 4-(3-Bromo-5-fluorophenyl)piperazin-1-ol meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H12BrFN2O |
| Molecular Weight | 275.12 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1994 |
| Halogen Content | F/Br-containing |
| Nitrogen Atoms | 2 |
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Recommended Standards
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- 4-Bromo-3-(methylsulfonyl)-1H-indazole (CAS 1823338-27-7)
- N-Boc-6-hydroxy-DL-norleucine Methyl Ester (CAS 81505-49-9)
- N-(5-Bromo-2-methylphenyl)acetamide (CAS 116436-10-3)
- 2-(tert-Butyl) 6-methyl 1,3-dihydro-2H-pyrrolo[3,4-c]pyridine-2,6-dicarboxylate (CAS 720720-29-6)
- 1-(4-Fluoro-2-nitrophenyl)piperidine (CAS 719-70-0)
- (1S,3S)-cyclopentane-1,3-diamine;dihydrochloride (CAS 2725774-24-1)
- Ethyl 2-((3-nitropyridin-2-yl)thio)acetate (CAS 24100-65-0)
- 2-Methylenecyclopropanecarboxaldehyde (CAS 142423-24-3)
- 4-methyl-1H,2H,3H,4H-pyrido[2,3-b]pyrazin-2-one (CAS 1314974-86-1)
- Pyridine (CAS CATO-LCEM500820-ME)
- Semaglutide impurity 65 (CAS CATO-C4X-222665)
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