4-(Difluoromethyl)-5-iodo-6-(4-methylpiperazin-1-yl)pyrimidine CAS 1706441-75-9
| CAS No. | 1706441-75-9 |
| Molecular Formula | C10H13F2IN4 |
| Molecular Weight | 354.14 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO supplies 4-(Difluoromethyl)-5-iodo-6-(4-methylpiperazin-1-yl)pyrimidine (CAS 1706441-75-9), a certified reference material (molecular formula C10H13F2IN4, MW 354.14 g/mol) for analytical method development and quality control.
4-(Difluoromethyl)-5-iodo-6-(4-methylpiperazin-1-yl)pyrimidine (C10H13F2IN4) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/iodine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C10H13F2IN4 |
| Molecular Weight | 354.14 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1994 |
| Halogen Content | F/I-containing |
| Nitrogen Atoms | 4 |
Related Difluoromethyl Standards
- 2-(Difluoromethyl)-3-iodopyridine-6-sulfonyl chloride (CAS 1804688-14-9)
- 2-(Difluoromethyl)-5-iodopyridine-4-sulfonyl chloride (CAS 1805034-56-3)
- 4-(Difluoromethyl)-2-iodopyridine-3-sulfonyl chloride (CAS 1805313-61-4)
- 2-(Difluoromethyl)-4-iodopyridine-6-sulfonyl chloride (CAS 1805327-93-8)
- 2-(Difluoromethyl)-4-iodopyridine-5-sulfonyl chloride (CAS 1806772-67-7)
- 2-(Difluoromethyl)-3-iodopyridine-5-sulfonyl chloride (CAS 1806773-81-8)
- 2-(Difluoromethyl)-3-hydroxy-4-iodo-6-(trifluoromethoxy)pyridine (CAS 1803941-55-0)
- 2-(Difluoromethyl)-3-hydroxy-6-iodo-5-(trifluoromethoxy)pyridine (CAS 1804311-77-0)
Recommended Standards
- Benzyl (4-iodopyridin-2-yl)carbamate (CAS 1624261-09-1)
- 1,6-Divinylperfluorohexane (CAS 1800-91-5)
- 2,5-Dibromo-3-octylthiophene (CAS 149703-84-4)
- (E)-3-nitrobenzaldehyde O-((3,4-dichlorophenyl)carbamoyl) oxime (CAS 39089-88-8)
- 3-(3,4-dichlorophenoxy)propan-1-ol (CAS 81785-47-9)
- 7-Iodo-1H-indazol-6-ol (CAS 1190314-62-5)
- Ethyl 3-(5-formyl-2-methoxyphenoxy)propanoate (CAS 1443312-68-2)
- 2,3-Dihydrothieno[3,4-b][1,4]dioxin-5-amine (CAS 932371-14-7)
- Ethyl 2-amino-2-(2-(trifluoromethyl)phenyl)acetate (CAS 500772-65-6)
- (R)-3-Amino-3-(3-bromophenyl)propan-1-ol (CAS 1213827-47-4)
- 2-(Chloromethyl)-1-(4-methoxyphenyl)-1H-benzo[d]imidazole (CAS 869716-13-2)
- 2-(5-Butyl-4-imino-1-phenyl-4,5-dihydro-1H-pyrazolo[3,4-d]pyrimidin-3-yl)acetonitrile (CAS 6332-59-8)
- Benzo[e][1,2,4]triazin-6-amine (CAS 96461-65-3)
- Thymopoietin II Peptide Fragment (CAS 56795-64-3)
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