5-(3-Ethoxy-4-((2-fluorobenzyl)oxy)-5-iodophenyl)-1,3,4-oxadiazol-2-amine CAS 1706445-07-9
| CAS No. | 1706445-07-9 |
| Molecular Formula | C17H15FIN3O3 |
| Molecular Weight | 455.22 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 5-(3-Ethoxy-4-((2-fluorobenzyl)oxy)-5-iodophenyl)-1,3,4-oxadiazol-2-amine is closely related to a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine/iodine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
5-(3-Ethoxy-4-((2-fluorobenzyl)oxy)-5-iodophenyl)-1,3,4-oxadiazol-2-amine (CAS 1706445-07-9), molecular formula C17H15FIN3O3 and molecular weight 455.22 g/mol, is a CATO reference standard with documented purity and traceability.
Structurally, 5-(3-Ethoxy-4-((2-fluorobenzyl)oxy)-5-iodophenyl)-1,3,4-oxadiazol-2-amine (C17H15FIN3O3) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine/iodine substitution. The molecule exhibits a degree of unsaturation (DBE) of 11.0, corresponding to approximately 11 ring(s) or double-bond equivalent(s). With a molecular weight of 455.22 g/mol, it falls into the moderately-high-molecular-weight range. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 5-(3-Ethoxy-4-((2-fluorobenzyl)oxy)-5-iodophenyl)-1,3,4-oxadiazol-2-amine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C17H15FIN3O3 |
| Molecular Weight | 455.22 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1994 |
| Halogen Content | F/I-containing |
| Nitrogen Atoms | 3 |
Related Ethoxy Standards
- 5-(3-Ethoxy-4-((4-fluorobenzyl)oxy)-5-iodophenyl)-1,3,4-oxadiazol-2-amine (CAS 1706445-06-8)
- 2-(2-Ethoxy-4-formyl-6-iodophenoxy)-N-(2-methoxyphenyl)acetamide (CAS 832673-61-7)
- 2-(1-(4-Ethoxy-4-oxobutyl)-7-hydroxy-2,2,4-trimethyl-1,2,3,4-tetrahydroquinoline-6-carbonyl)benzoic acid (CAS 2031170-84-8)
- 2-(2-Ethoxy-4-formyl-6-iodophenoxy)-N-phenethylacetamide (CAS 486994-22-3)
- 2-((6-Ethoxy-2-phenylquinazolin-4-yl)thio)-N-mesitylacetamide (CAS 332948-16-0)
- 5-(3-Ethoxy-4-hydroxyphenyl)-4-(3-fluoro-4-methylbenzoyl)-1-(furan-2-ylmethyl)-3-hydroxy-1H-pyrrol-2(5H)-one (CAS 618075-77-7)
- Ethyl 2-ethoxy-5-(4-ethoxy-3-ethoxycarbonylphenyl)sulfonylbenzoate (CAS 1391053-18-1)
- 6-Benzyl-2-(3-ethoxy-4-propoxybenzylidene)-2H-thiazolo[3,2-b][1,2,4]triazine-3,7-dione (CAS 617694-38-9)
Recommended Standards
- 3-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]methyl}-1-[(4-chlorophenyl)methyl]-2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-carbonitrile (CAS 338399-22-7)
- 1-(2,6-Dichlorobenzyl)-4-(3-(2,4-dichlorophenyl)-1H-pyrazol-5-yl)piperidine (CAS 321998-73-6)
- N-[2-(2,6-dioxo-3-piperidyl)-1,3-dioxo-isoindolin-4-yl]-3-iodo-propanamide (CAS 2703834-47-1)
- 3-Iodo-5-methoxy-4-(2-oxo-2-(phenethylamino)ethoxy)benzoic acid (CAS 709003-72-5)
- 4-(p-Tolyl)-1H-imidazole (CAS 670-91-7)
- 4-(Aminomethyl)-5-methylthiazol-2-amine (CAS 1378858-51-5)
- N-[2-(1H-Indol-3-yl)ethyl]-4-methylpent-2-enamide (CAS 1020251-92-6)
- Alogliptin Impurity 27 (CAS CATO-C4X-109927)
- 2-Chloro-N-methoxy-N-methyl-5-nitrobenzene-1-sulfonamide (CAS 1184485-21-9)
- 5,8-Dihydroxy-2-phenethyl-4H-chromen-4-one (CAS 69809-24-1)
- 2-Chloro-3-fluoro-6-methoxy-benzaldehyde (CAS 1263378-40-0)
- N-(3-chloro-2-methylphenyl)-4-fluorobenzamide (CAS 331270-53-2)
- 1-(2-Hydroxy-5-methylphenyl)-3-methylbutan-1-one (CAS 55813-81-5)
- Serpent Peptide 2AcOH (CAS 823202-99-9(free base))
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