5-(4-((2-Chloro-4-fluorobenzyl)oxy)-3-iodophenyl)-1,3,4-oxadiazol-2-amine CAS 1706445-16-0
| CAS No. | 1706445-16-0 |
| Molecular Formula | C15H10ClFIN3O2 |
| Molecular Weight | 445.61 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 5-(4-((2-Chloro-4-fluorobenzyl)oxy)-3-iodophenyl)-1,3,4-oxadiazol-2-amine.
5-(4-((2-Chloro-4-fluorobenzyl)oxy)-3-iodophenyl)-1,3,4-oxadiazol-2-amine (CAS 1706445-16-0) is a high-purity analytical reference standard with the molecular formula C15H10ClFIN3O2 and a molecular weight of 445.61 g/mol.
Structurally, 5-(4-((2-Chloro-4-fluorobenzyl)oxy)-3-iodophenyl)-1,3,4-oxadiazol-2-amine (C15H10ClFIN3O2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine/iodine substitution. The molecule exhibits a degree of unsaturation (DBE) of 11.0, corresponding to approximately 11 ring(s) or double-bond equivalent(s). With a molecular weight of 445.61 g/mol, it falls into the moderately-high-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 5-(4-((2-Chloro-4-fluorobenzyl)oxy)-3-iodophenyl)-1,3,4-oxadiazol-2-amine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C15H10ClFIN3O2 |
| Molecular Weight | 445.61 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1994 |
| Halogen Content | F/Cl/I-containing |
| Nitrogen Atoms | 3 |
Related Chloro Standards
- 3-Chloro-2-[(1Z)-[2-(2,4-dichlorophenyl)hydrazin-1-ylidene](pyridin-3-yl)methyl]-5-(trifluoromethyl)pyridine (CAS 306977-31-1)
- 1-Chloro-3,5-Bis-(4-chlorobenzoyl)-2-deoxy-D-ribofuranose (CAS 21740-23-8)
- 3-Chloro-5-(trifluoromethyl)-2-[(4-{[3-(trifluoromethyl)phenyl]methoxy}phenyl)methyl]pyridine (CAS 339106-64-8)
- 3-Chloro-4-pyridylcycloheptyl ketone (CAS 898785-24-5)
- 5-[2-[4-Chloro-2-(Trifluoromethyl)Phenyl]Hydrazinyl]-6-Imino-4-Oxonaphthalene-2-Sulfonic Acid (CAS 3836-78-0)
- (E)-1-(2-((3-chloro-5-(trifluoromethyl)pyridin-2-yl)amino)ethyl)-5-(3-(dimethylamino)acryloyl)-3-methylpyrimidine-2,4(1H,3H)-dione (CAS 338770-12-0)
- 3-(3-(4-(2-Chloro-4-nitrophenoxy)butyl)ureido)benzene-1-sulfonyl fluoride (CAS 25313-31-9)
- 4-(3-(3-(2-Chloro-4-nitrophenoxy)propyl)ureido)-2-methylbenzene-1-sulfonyl fluoride (CAS 25313-30-8)
Recommended Standards
- (R)-2-(3-(Furan-2-yl)acrylamido)-3-((3,7,11-trimethyldodeca-2,6,10-trien-1-yl)thio)propanoic acid (CAS 165245-19-2)
- HX 630-d4 (CAS 1794787-53-3)
- AEE 788 D5 (CAS 1292840-54-0)
- 2-((tert-Butoxycarbonyl)amino)-3-((tert-butyldimethylsilyl)oxy)-3-(naphthalen-1-yl)propanoic acid (CAS 1263093-88-4)
- 4-(Difluoromethyl)-6-iodo-5-(trifluoromethyl)nicotinaldehyde (CAS 1807020-29-6)
- Ethyl 4-hydroxy-7-(trifluoromethoxy)quinoline-3-carboxylate (CAS 53985-73-2)
- [3-(4-methylphenyl)-4,5-dihydro-1,2-oxazol-5-yl]methanamine hydrochloride (CAS 1803585-57-0)
- (2-Bromopyridin-3-yl)methanamine xhydrochloride (CAS 870064-21-4)
- (R)-3-amino-4-(thiophen-3-yl)butanoic acid hydrochloride (CAS 332061-93-5)
- 2-(1-((tert-Butoxycarbonyl)amino)cyclobutyl)acetic acid (CAS 249762-02-5)
- Macitentan Impurity 43 (CAS CATO-C4X-117543)
- 3-(3-Phenylallyl)pentane-2,4-dione (CAS 29638-71-9)
- 2-(3-Bromo-2,2-dimethylpropyl)-1,3,5-trimethylbenzene (CAS 1483730-36-4)
- Exenatide (CAS 141758-74-9)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com