7,8-Difluoro-1,2,3,4-tetrahydroquinoline-3-carboxylic acid CAS 1706448-80-7
| CAS No. | 1706448-80-7 |
| Molecular Formula | C10H9F2NO2 |
| Molecular Weight | 213.18 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Structurally, 7,8-Difluoro-1,2,3,4-tetrahydroquinoline-3-carboxylic acid (C10H9F2NO2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 6.0, corresponding to approximately 6 ring(s) or double-bond equivalent(s). With a molecular weight of 213.18 g/mol, it falls into the medium-molecular-weight range. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
7,8-Difluoro-1,2,3,4-tetrahydroquinoline-3-carboxylic acid (CAS 1706448-80-7), molecular formula C10H9F2NO2 and molecular weight 213.18 g/mol, is a CATO reference standard with documented purity and traceability.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 7,8-Difluoro-1,2,3,4-tetrahydroquinoline-3-carboxylic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H9F2NO2 |
| Molecular Weight | 213.18 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1994 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Difluoro Standards
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- 2,6-Difluoro-N-(oxiran-2-ylmethyl)benzamide (CAS 1437457-78-7)
- 5,6-Difluoro-1,2,3,4-tetrahydroquinoline-2-carboxylic acid (CAS 1706428-68-3)
- 7,8-Difluoro-2,2-dimethyl-2H-benzo[b][1,4]oxazin-3(4H)-one (CAS 885517-43-1)
- 3,3-Difluoro-2-oxoindoline-5-carboxylic acid (CAS 1706456-26-9)
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Recommended Standards
- 7-(Difluoromethyl)-7,8-dihydroquinoline-2,5(1H,6H)-dione (CAS 1706448-28-3)
- 6-Cyclopropyl-2-(difluoromethyl)nicotinic acid (CAS 1707603-54-0)
- 2-Amino-7-(difluoromethyl)-7,8-dihydroquinazolin-5(6H)-one (CAS 1706441-54-4)
- 2-(6-Amino-5-(difluoromethyl)-4-methoxypyridin-2-yl)acetonitrile (CAS 1803674-21-6)
- 3-(2,4-Dimethylphenyl)-5-phenyl-1H-1,2,4-triazole (CAS 85303-90-8)
- 2-(Benzyloxy)tetrahydrofuran (CAS 1927-58-8)
- ethyl 3-(chloromethyl)-5-methyl-1,2-oxazole-4-carboxylate (CAS 266341-73-5)
- Ethyl 4-(2-chloroacetyl)piperazine-1-carboxylate (CAS 40981-17-7)
- 3-(dihydroxyboranyl)propanoic acid (CAS 220999-41-7)
- Methyl (s)-2-amino-4-(methylselanyl)butanoate (CAS 821766-18-1)
- 1-(6-Chloropyridin-3-yl)ethan-1-amine hydrochloride (CAS 1955499-39-4)
- 6-benzyl-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidin-2-amine (CAS 949654-76-6)
- Metaraminol Impurity 39 (CAS CATO-C4X-225239)
- [D-His1]-Semaglutide (CAS CATO-C4X-2226127)
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