Methyl 4-((2-chloro-4-fluorobenzyl)oxy)-3-ethoxybenzoate CAS 1706450-37-4
| CAS No. | 1706450-37-4 |
| Molecular Formula | C17H16ClFO4 |
| Molecular Weight | 338.76 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Methyl 4-((2-chloro-4-fluorobenzyl)oxy)-3-ethoxybenzoate (CAS 1706450-37-4), molecular formula C17H16ClFO4 and molecular weight 338.76 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of Methyl 4-((2-chloro-4-fluorobenzyl)oxy)-3-ethoxybenzoate (C17H16ClFO4) is characterized by a flavonoid core, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a certified reference material (CRM), Methyl 4-((2-chloro-4-fluorobenzyl)oxy)-3-ethoxybenzoate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C17H16ClFO4 |
| Molecular Weight | 338.76 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1994 |
| Halogen Content | F/Cl-containing |
Related Methyl Standards
- 3-Chloro-5-ethoxy-4-((4-fluorobenzyl)oxy)benzohydrazide (CAS 1706443-45-9)
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- 3-Chloro-5-ethoxy-4-((3-fluorobenzyl)oxy)benzohydrazide (CAS 1706447-54-2)
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Recommended Standards
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- 5-(3-Chlorophenyl)-1-[(4-fluorophenyl)methyl]-2-oxo-1,2-dihydropyridine-3-carbonitrile (CAS 338955-47-8)
- N-[2-(1H-Indol-3-yl)ethyl]-2,3,4,5,6-pentamethylbenzenesulfonamide (CAS 661475-56-5)
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- 5-Chloro-2-(trifluoromethoxy)pyrimidine (CAS 1261432-62-5)
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- (3-Formyl-1-methyl-1H-indol-2-yl) zinc pivalate (1.00 mmol/g) (CAS 2021255-90-1)
- Peptide 432 (CAS CATO-CPTD788432)
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