2,6-Difluoro-3-methoxybenzenesulfonyl chloride CAS 1706458-18-5
| CAS No. | 1706458-18-5 |
| Molecular Formula | C7H5ClF2O3S |
| Molecular Weight | 242.63 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
2,6-Difluoro-3-methoxybenzenesulfonyl chloride (CAS 1706458-18-5), molecular formula C7H5ClF2O3S and molecular weight 242.63 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, an aromatic ring system, 2,6-Difluoro-3-methoxybenzenesulfonyl chloride is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 242.63 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 2,6-Difluoro-3-methoxybenzenesulfonyl chloride under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C7H5ClF2O3S |
| Molecular Weight | 242.63 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1994 |
| Halogen Content | F/Cl-containing |
| Sulfur Atoms | 1 |
Related Difluoro Standards
- 2,4-Difluoro-6-methoxybenzenesulfonyl chloride (CAS 1162257-25-1)
- 3,6-Difluoro-2-methoxybenzene-1-sulfonyl chloride (CAS 1162257-28-4)
- 3,5-Difluoro-4-methoxybenzenesulfonyl chloride (CAS 1178236-98-0)
- 2,6-Difluoro-4-methoxybenzenesulfonyl chloride (CAS 1178498-86-6)
- 2,3-Difluoro-6-methoxybenzenesulfonyl chloride (CAS 1208074-96-7)
- 2,5-Difluoro-4-methoxybenzene-1-sulfonyl chloride (CAS 1208075-47-1)
- 3,5-Difluoro-2-methoxybenzenesulfonyl chloride (CAS 1233509-72-2)
- 4,5-Difluoro-2-methoxybenzene-1-sulfonyl chloride (CAS 1261825-36-8)
Recommended Standards
- 1-(2-chloro-5-fluoro-phenyl)hexahydropyrimidine-2,4-dione (CAS 1694302-49-2)
- 2,4-Difluoro-3-methoxybenzenesulfonyl chloride (CAS 1706458-65-2)
- 1-(3-chloro-5-fluoro-phenyl)hexahydropyrimidine-2,4-dione (CAS 1691633-40-5)
- Methyl 4-chloro-3-(difluoromethoxy)thiophene-2-carboxylate (CAS 1707581-59-6)
- n-Methyl-n-(styrylsulfonyl)glycine (CAS 851879-20-4)
- 2-(3-Fluoro-4-methoxy-5-(trifluoromethyl)phenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS 2121513-13-9)
- 6,7-Dihydro-5H-cyclopenta[b]pyridine-6-carboxylic acid hydrochloride (CAS 220001-82-1)
- 3-Bromo-7-(difluoromethyl)imidazo[1,2-a]pyridine (CAS 1781507-64-9)
- 4-(2-Hydroxyethyl)tetrahydro-2H-pyran-4-yl 4-methylbenzenesulfonate (CAS 1135038-81-1)
- 2-Ethyl-3-nitropyridine (CAS 1346534-62-0)
- ethyl 2-methyl-4H-thieno[3,2-b]pyrrole-5-carboxylate (CAS 238749-54-7)
- (1S,3R)-3-fluorocyclohexan-1-amine hydrochloride (CAS 2227199-22-4)
- 2-(4-Phenyl-1,3-thiazol-2-yl)acetohydrazide (CAS 871547-65-8)
- Semaglutide impurity 37 (CAS CATO-C4X-222637)
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