4-Fluoro-3-methyl-5-(trifluoromethyl)benzenesulfonyl chloride CAS 1706458-75-4
| CAS No. | 1706458-75-4 |
| Molecular Formula | C8H5ClF4O2S |
| Molecular Weight | 276.64 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
4-Fluoro-3-methyl-5-(trifluoromethyl)benzenesulfonyl chloride (CAS 1706458-75-4) is a high-purity analytical reference standard with the molecular formula C8H5ClF4O2S and a molecular weight of 276.64 g/mol.
Structurally, 4-Fluoro-3-methyl-5-(trifluoromethyl)benzenesulfonyl chloride (C8H5ClF4O2S) contains a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, an aromatic ring system. The molecule exhibits a degree of unsaturation (DBE) of 4.0, corresponding to approximately 4 ring(s) or double-bond equivalent(s). With a molecular weight of 276.64 g/mol, it falls into the medium-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 4-Fluoro-3-methyl-5-(trifluoromethyl)benzenesulfonyl chloride under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C8H5ClF4O2S |
| Molecular Weight | 276.64 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1994 |
| Halogen Content | F/Cl-containing |
| Sulfur Atoms | 1 |
Related Fluoro Standards
- (2-Fluoro-4-(trifluoromethyl)phenyl)methanesulfonyl chloride (CAS 1357624-06-6)
- 2-Fluoro-5-methyl-4-(trifluoromethyl)benzenesulfonyl chloride (CAS 1706431-05-1)
- 3-Fluoro-4-methyl-5-(trifluoromethyl)benzenesulfonyl chloride (CAS 1706451-99-1)
- (2-Fluoro-5-(trifluoromethyl)phenyl)methanesulfonyl chloride (CAS 501697-75-2)
- 2-Fluoro-4-methylbenzenesulfonyl chloride (CAS 827614-35-7)
- 1-Fluoro-4-(trans-4-heptylcyclohexyl)benzene (CAS 76802-59-0)
- 2-Fluoro-N-(1,7,7-trimethylbicyclo[2.2.1]Heptan-2-yl)isonicotinamide (CAS 1291647-45-4)
- 8-Fluoro-1-(2-(piperidin-1-yl)ethyl)-3,4-dihydroquinolin-2(1H)-one (CAS 1373391-80-0)
Recommended Standards
- (1-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)-1H-pyrrol-2-yl)methanol (CAS 321430-86-8)
- (5-(2-Chloro-5-(trifluoromethyl)phenyl)furan-2-yl)methanol (CAS 773869-11-7)
- N-[3-Chloro-5-(trifluoromethyl)-2-pyridinyl]-N-(2-furylmethyl)amine (CAS 1036578-95-6)
- 4-Chloro-5-(4-methoxyphenyl)-3-trifluomethylpyrazole (CAS 740807-64-1)
- {3-methoxybicyclo[1.1.1]pentan-1-yl}methanamine hydrochloride (CAS 2231675-05-9)
- Damascenon (CAS 23726-93-4)
- tert-Butyl 3-(((4-methylpyridin-2-yl)amino)methyl)piperidine-1-carboxylate (CAS 939986-31-9)
- 4-Amino-2-fluoro-3-iodophenol (CAS 1934486-71-1)
- 3-[(benzylsulfanyl)methyl]-1-benzofuran-2-carboxylic acid (CAS 565174-28-9)
- 3-Hydroxy-5-(hydroxymethyl)isonicotinaldehyde (CAS 15031-18-2)
- 4-Propoxypicolinimidamide hydrochloride (CAS 1179362-47-0)
- 5-Bromo-7-methoxy-3-methylquinolin-2(1H)-one (CAS 2763823-87-4)
- (+)-Angelmarin (CAS 876384-53-1)
- Angiotensin II Antipeptide (CAS 121379-63-3)
Why CATO?
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