1-(Azetidin-3-yl)-4-fluoro-piperidine ditrifluoroacetate CAS 1706463-13-9
| CAS No. | 1706463-13-9 |
| Molecular Formula | C8H15FN2 |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 1-(Azetidin-3-yl)-4-fluoro-piperidine ditrifluoroacetate.
CATO supplies 1-(Azetidin-3-yl)-4-fluoro-piperidine ditrifluoroacetate (CAS 1706463-13-9), a certified reference material (molecular formula C8H15FN2C2HF3O2, MW 272.24 g/mol) for analytical method development and quality control.
The molecular framework of 1-(Azetidin-3-yl)-4-fluoro-piperidine ditrifluoroacetate (C8H15FN2C2HF3O2) is characterized by an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C8H15FN2 2*C2HF3O2 |
| Molecular Weight | 272.24 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 2.0 |
| CAS Registry Year (est.) | 1994 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Azetidin Standards
- 4-(Azetidin-1-yl)cyclohexan-1-amine dihydrochloride (CAS 1001347-27-8)
- 4-(Azetidin-1-ylmethyl)-1H-indole (CAS 1001395-40-9)
- 2-(Azetidin-1-yl)acetic acid (CAS 1008304-81-1)
- Azetidin-3-yl methylcarbamate hydrochloride (CAS 1009368-29-9)
- 5-(Azetidin-3-yl)-2-methyl-tetrazole (CAS 1009409-58-8)
- 2-((Azetidin-3-yloxy)methyl)-5-methyl-1,3,4-oxadiazole (CAS 1009409-61-3)
- Azetidin-3-yl methylcarbamate (CAS 1009409-62-4)
- 1-(Azetidin-3-ylmethyl)piperidine (CAS 1012784-24-5)
Recommended Standards
- 3-(Cyclopropylsulfamoyl)-4-fluorobenzoic acid (CAS 926252-91-7)
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- N2-(3-methoxypropyl)-5-nitropyridine-2,6-diamine (CAS 1525527-26-7)
- Dibenzo[b,e][1,4]dioxine-2,3,7,8-tetraamine tetrahydrochloride (CAS 16435-75-9)
- Carquejol (CAS 23734-06-7)
- 2-Ethyl-5-oxo-1-phenyl-2,5-dihydro-1H-pyrazole-3-carboxamide (CAS 133954-33-3)
- 4-(Cyclopropylmethoxy)-2-hydroxy-N-methylbenzamide (CAS 1243379-32-9)
- 5-(4-Ethoxy-3-methoxyphenyl)-3-methyl-1H-1,2,4-triazole (CAS 1416338-41-4)
- trans-2-(4-(Dimethylamino)phenyl)cyclohexanol (CAS 933674-51-2)
- Semaglutide Impurity 1(OtBu-Ste-D-γGlu(OtBu)-AEEA-AEEA-OH) (CAS CATO-C4X-22261)
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