8-Bromo-6-methylpyrido[4,3-d]pyrimidin-5(6H)-one CAS 1706751-60-1
| CAS No. | 1706751-60-1 |
| Molecular Formula | C8H6BrN3O |
| Molecular Weight | 240.06 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
8-Bromo-6-methylpyrido[4,3-d]pyrimidin-5(6H)-one (CAS 1706751-60-1) is a high-purity analytical reference standard with the molecular formula C8H6BrN3O and a molecular weight of 240.06 g/mol.
The molecular framework of 8-Bromo-6-methylpyrido[4,3-d]pyrimidin-5(6H)-one (C8H6BrN3O) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, bromine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C8H6BrN3O |
| Molecular Weight | 240.06 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1994 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 3 |
Related Bromo Standards
- 3-Bromo-1H-indazole-7-carboxamide (CAS 1040101-02-7)
- 3-bromo-5-(5-methyl-1,3,4-oxadiazol-2-yl)pyridine (CAS 1159979-16-4)
- 7-Bromo-2-methylpyrido[3,2-d]pyrimidin-4-ol (CAS 1228666-56-5)
- 4-Bromo-1-(pyrimidin-2-yl)-1H-pyrazol-3-amine (CAS 1247771-25-0)
- (Z)-5-bromo-3-hydrazonoindolin-2-one (CAS 1268694-53-6)
- 3-Bromo-5-(3-methyl-1,2,4-oxadiazol-5-yl)pyridine (CAS 1283108-13-3)
- 6-Bromo-2-methylpyrido[2,3-d]pyrimidin-4(3H)-one (CAS 1361459-59-7)
- 1-(6-Bromo-1H-pyrazolo[4,3-b]pyridin-1-yl)ethanone (CAS 1383735-65-6)
Recommended Standards
- 6-Bromo-1H-pyrrolo[3,2-c]pyridine-3-carboxamide (CAS 1690363-15-5)
- 1-(3-Bromo-1H-pyrazolo[4,3-b]pyridin-1-yl)ethanone (CAS 1779130-00-5)
- 5-Bromo-1H-pyrrolo[2,3-c]pyridine-2-carboxamide (CAS 1690342-33-6)
- 5-Bromo-1H-indazole-3-carboxamide (CAS 1799421-04-7)
- 3-(5-Oxo-4,5-dihydro-1H-pyrazol-1-yl)benzenesulfonic acid (CAS 90730-07-7)
- N-(4-fluorobenzyl)pyrrolidine-2-carboxamide (CAS 1491643-53-8)
- N-(3-(2-Phenyl-1H-imidazol-1-yl)propyl)-2-(m-tolyl)acetamide (CAS 1421510-27-1)
- 2-Formyl-4-methylthiophene-3-carboxylic acid (CAS 2167543-72-6)
- 1-(3-Methoxypropyl)-2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-carbonitrile (CAS 338399-18-1)
- 5-Amino-1-(2,3,5-tri-O-acetyl-β-D-ribofuranosyl)-imidazole-4-carboxamide (CAS 23274-21-7)
- Methyl 3-methyl-1H-pyrazolo[4,3-b]pyridine-5-carboxylate (CAS 1206983-99-4)
- Tert-butyl (2-(1H-imidazol-5-yl)ethyl)carbamate (CAS 98870-64-5)
- Hexahydropyrrolo[3,2-b]pyrrol-2(1H)-one (CAS 1422140-08-6)
- CBP501 Affinity Peptide trifluoroacetate salt (CAS 1351804-17-5)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com