2-(4,4-Difluoropiperidin-1-yl)-3-fluoropyridine CAS 1707357-97-8
| CAS No. | 1707357-97-8 |
| Molecular Formula | C10H11F3N2 |
| Molecular Weight | 216.20 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies 2-(4,4-Difluoropiperidin-1-yl)-3-fluoropyridine (CAS 1707357-97-8), a certified reference material (molecular formula C10H11F3N2, MW 216.20 g/mol) for analytical method development and quality control.
2-(4,4-Difluoropiperidin-1-yl)-3-fluoropyridine (C10H11F3N2) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C10H11F3N2 |
| Molecular Weight | 216.20 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1994 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Difluoropiperidin Standards
- 2-(4,4-Difluoropiperidin-1-yl)-5-fluoropyridine (CAS 1707365-61-4)
- 2-(3,3-Difluoropiperidin-1-yl)-5-fluoropyridine (CAS 1707391-19-2)
- 2-(4,4-Difluoropiperidin-1-yl)-6-fluoropyridine (CAS 1707604-83-8)
- 1779119-11-7 3-(4,4-Difluoropiperidin-1-yl)-5-fluoropyridine (CAS 1779119-11-7)
- 2-(3,3-Difluoropiperidin-1-yl)-3-fluoropyridine 1779120-24-9 (CAS 1779120-24-9)
- 2-(3,3-Difluoropiperidin-1-yl)-6-fluoropyridine (CAS 1779127-81-9)
- 1779133-26-4 3-(3,3-Difluoropiperidin-1-yl)-5-fluoropyridine (CAS 1779133-26-4)
- (S)-5-(4,4-Difluoropiperidin-3-yl)pyridin-2(1H)-one (CAS 2767114-90-7)
Recommended Standards
- 1-[3-(trifluoromethyl)phenyl]butan-1-one (CAS 1705-16-4)
- 5-Methyl-2-(pyrazin-2-yl)pyrimidine-4-carboxylic acid (CAS 1690946-58-7)
- 3-(Pyrrolidin-1-yl)-4-(trifluoromethyl)pyridine (CAS 1707367-77-8)
- N-(4-Nitrophenyl)pyrimidin-5-amine (CAS 157911-59-6)
- 82436-77-9 Bis(sulfosuccinimidyl) suberate sodium salt Suberic acid bis(3-sulfo-N-hydroxysuccinimide ester) sodium salt bis(sulfosuccinimidyl) suberate, sodium salt bis(sulfosuccinimidyl)suberate bis-sulfo-succinimidyl suberate bs3 bs3 bsss octanedioic acid bis-(2,5-dioxo-3-sulfo-pyrrolidin-1-yl) ester sodium salt suberate bis(sulfosuccinimidyl) sodium salt suberic acid bis(3-sulfo-n-hydroxysuccinimide ester)sodium salt (CAS 82436-77-9)
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- (2-Chloro-4-(6-methylpyrazin-2-yl)phenyl)boronic acid (CAS 1648864-28-1)
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- Peptide-GMF (CAS CATO-CPTD788469)
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