4-(Cyclobutylmethoxy)-3,5-difluoroaniline CAS 1707369-83-2
| CAS No. | 1707369-83-2 |
| Molecular Formula | C11H13F2NO |
| Molecular Weight | 213.22 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 4-(Cyclobutylmethoxy)-3,5-difluoroaniline (C11H13F2NO) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
4-(Cyclobutylmethoxy)-3,5-difluoroaniline (CAS 1707369-83-2) is a high-purity analytical reference standard with the molecular formula C11H13F2NO and a molecular weight of 213.22 g/mol.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C11H13F2NO |
| Molecular Weight | 213.22 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1994 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Cyclobutylmethoxy Standards
- 2-(cyclobutylmethoxy)ethane-1-sulfonyl chloride (CAS 1909318-83-7)
- 4-(cyclobutylmethoxy)cyclohexane-1-carboxylic acid (CAS 1601147-11-8)
- 6-Cyclobutylmethoxy-indan-1-one (CAS 1383985-15-6)
- 2-(Cyclobutylmethoxy)-3-nitropyridine (CAS 1049729-98-7)
- 2-(Cyclobutylmethoxy)pyrimidine-5-carboxylic acid (CAS 1402232-52-3)
- 6-(Cyclobutylmethoxy)pyrimidine-4-carboxylic acid (CAS 1439897-87-6)
- 5-(Cyclobutylmethoxy)pyrazine-2-carboxylic acid (CAS 1609462-20-5)
- 6-(Cyclobutylmethoxy)pyrazine-2-carboxylic acid (CAS 1824271-85-3)
Recommended Standards
- 3-(Aminomethyl)-3-(3,5-difluorophenyl)cyclobutan-1-ol (CAS 1487947-01-2)
- 1-Benzyl-4,4-difluoropyrrolidin-3-ol (CAS 1776114-17-0)
- 3-(Aminomethyl)-3-(2,4-difluorophenyl)cyclobutan-1-ol (CAS 1482984-83-7)
- Di<I>tert</I>butyldichlorosilane (CAS 18395-90-9)
- Tert-butyl 5-hydroxy-2-azabicyclo[4.1.0]Heptane-2-carboxylate (CAS 1544407-76-2)
- 4-{[(4-chlorophenyl)sulfanyl]methyl}benzoic acid (CAS 88382-51-8)
- 4-Benzoylpyrimidine (CAS 68027-80-5)
- 1-(2-Methoxyethyl)-3-(3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)urea (CAS 874299-26-0)
- 1-Bromo-2-(ethylsulfanyl)ethane (CAS 35420-95-2)
- 2-((tert-Butoxycarbonyl)amino)-3-(4-hydroxy-3-methoxyphenyl)propanoic acid (CAS 129048-72-2)
- 6-Benzylquinoline (CAS 54884-99-0)
- 4-[(Cyclopropylcarbonyl)amino]-3-fluorobenzoic Acid (CAS 1314406-43-3)
- 6-(4-Bromo-2-fluorophenoxy)hexanenitrile (CAS 1443342-04-8)
- Erythropoietin Mimetic Peptide Sequence 20 (CAS 203397-62-0)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com