3-(4,4-Difluoropiperidin-1-yl)-2-nitropyridine 1707373-89-4 CAS 1707373-89-4
| CAS No. | 1707373-89-4 |
| Molecular Formula | C10H11F2N3O2 |
| Molecular Weight | 243.21 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 3-(4,4-Difluoropiperidin-1-yl)-2-nitropyridine 1707373-89-4.
3-(4,4-Difluoropiperidin-1-yl)-2-nitropyridine 1707373-89-4 (CAS 1707373-89-4) is a high-purity analytical reference standard with the molecular formula C10H11F2N3O2 and a molecular weight of 243.21 g/mol.
The molecular framework of 3-(4,4-Difluoropiperidin-1-yl)-2-nitropyridine 1707373-89-4 (C10H11F2N3O2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 3-(4,4-Difluoropiperidin-1-yl)-2-nitropyridine 1707373-89-4 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H11F2N3O2 |
| Molecular Weight | 243.21 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1994 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Related Difluoropiperidin Standards
- 2-(4,4-Difluoropiperidin-1-yl)-5-nitropyridine (CAS 1258234-21-7)
- 3-(4,4-Difluoropiperidin-1-yl)-4-nitropyridine (CAS 1707373-92-9)
- 3-(3,3-Difluoropiperidin-1-yl)-4-nitropyridine 1707572-71-1 (CAS 1707572-71-1)
- 2-(3,3-Difluoropiperidin-1-yl)-5-nitropyridine (CAS 1707605-19-3)
- 3-(3,3-Difluoropiperidin-1-yl)-2-nitropyridine 1707706-70-4 (CAS 1707706-70-4)
- 2-(4,4-Difluoropiperidin-1-yl)-3-nitropyridine 1774896-15-9 (CAS 1774896-15-9)
- 2-(3,3-Difluoropiperidin-1-yl)-3-nitropyridine 1779124-55-8 (CAS 1779124-55-8)
- 2-(4,4-Difluoropiperidin-1-yl)-3-fluorobenzaldehyde (CAS 1707357-91-2)
Recommended Standards
- 1-(Furan-2-ylmethylene)-6-methylfuro[3,4-c]pyridine-3,4(1H,5H)-dione (CAS 160032-92-8)
- tert-Butyl 2-(2,6-Difluoro-3-pyridyl)-2-oxoacetate (CAS 155601-70-0)
- Pentanedioic acid 2,5-dioxopyrrolidin-1-yl ester methyl ester (CAS 1511700-07-4)
- 3-(4-Nitrophenoxy)benzaldehyde (CAS 17076-72-1)
- (3R,4S,5S,8S,9S,10R,13R,14S,17R)-4-Allyl-10,13-dimethyl-17-((R)-6-methylheptan-2-yl)hexadecahydro-1H-cyclopenta[a]phenanthren-3-ol (CAS 152755-31-2)
- (2R,3AS,9aR)-2-Benzyl-4-methyl-decahydro-1,4-diaza-cyclopentacyclooctene (CAS 1391573-68-4)
- 3-[(1E)-(Methoxyimino)methyl]-1,3-dihydro-2-benzothiophen-1-one (CAS 339114-66-8)
- imidazo[1,2-a]pyridin-6-ylmethanamine (CAS 132213-03-7)
- Zinc(II) 5-methyl-2-thioxo-2,3-dihydrobenzo[d]imidazol-1-ide (CAS 107370-15-0)
- 2-{[(4-fluorophenyl)methyl]sulfanyl}pyridine-3,5-dicarbonitrile (CAS 339010-75-2)
- Salicylic acid Impurity 12 (CAS 546-74-7)
- (2-Chloro-4-(thietan-3-ylamino)phenyl)methanol (CAS 1866708-03-3)
- 3-Difluoromethyl-2,5-dimethylanisole (CAS 1806277-85-9)
- Neuropeptide Y (13-36) (human, rat) (CAS 122341-40-6)
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