5-Chloro-3-(difluoromethoxy)benzofuran-2-carboxylic acid CAS 1707391-73-8
| CAS No. | 1707391-73-8 |
| Molecular Formula | C10H5ClF2O4 |
| Molecular Weight | 262.59 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 262.59 g/mol gives 5-Chloro-3-(difluoromethoxy)benzofuran-2-carboxylic acid distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
5-Chloro-3-(difluoromethoxy)benzofuran-2-carboxylic acid (CAS 1707391-73-8), molecular formula C10H5ClF2O4 and molecular weight 262.59 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 5-Chloro-3-(difluoromethoxy)benzofuran-2-carboxylic acid (C10H5ClF2O4) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 5-Chloro-3-(difluoromethoxy)benzofuran-2-carboxylic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C10H5ClF2O4 |
| Molecular Weight | 262.59 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1994 |
| Halogen Content | F/Cl-containing |
Related Chloro Standards
- 2-Chloro-4-(2,2,2-trifluoroethyl)-1-(trifluoromethyl)benzene (CAS 1099597-18-8)
- 4-Chloro-2-(2,2,2-trifluoroethyl)-1-(trifluoromethyl)benzene (CAS 1099597-50-8)
- 1-Chloro-2-(2,2,2-trifluoroethyl)-4-(trifluoromethyl)benzene (CAS 1099597-65-5)
- 1-Chloro-2-methyl-4,5-bis(trifluoromethyl)benzene (CAS 1807097-15-9)
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Recommended Standards
- 2,5-Bis(trifluoromethyl)benzyl chloride (CAS 911060-71-4)
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- 3-Fluoro-2-(trifluoromethyl)benzenesulfonyl chloride (CAS 1214372-88-9)
- 1-(Chloromethyl)-2,4-bis(trifluoromethyl)benzene (CAS 195136-46-0)
- 4-(Chloromethyl)-3,5-dimethyl-1-phenyl-1H-pyrazole (CAS 1152595-49-7)
- 3-(Cyclohexylmethyl)-6-(methylthio)-1,3,5-triazine-2,4(1H,3H)-dione (CAS 52231-32-0)
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- (S)-1-(3,5-dimethoxyphenyl)-2,2-dimethylpropan-1-amine (CAS 1389389-65-4)
- 6-(4-Methoxyphenyl)-1-methylimidazo[4,5-b]pyridin-2-amine (CAS 1797911-00-2)
- 1-(4,5-dimethoxy-2-methylphenyl)ethan-1-amine hydrochloride (CAS 104174-56-3)
- Ethyl 4'-methyl-[1,1'-biphenyl]-4-carboxylate (CAS 106508-97-8)
- Ethyl 6-bromo-1H-indazole-3-carboxylate (CAS 885272-94-6)
- 2-(2-Iodo-1H-indol-3-yl)acetic acid (CAS 191674-47-2)
- Tau Peptide (45-73) (Exon 2/Insert 1 Domain) trifluoroacetate salt (CAS 2022956-54-1)
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